Advanced Stable Oral Suspensions of Baclofen

The present invention provides novel improvements to stable oral suspensions of baclofen, enhancing their stability, efficiency, and user experience. The inventive concept introduces a system, method, and composition that address the limitations of existing baclofen suspensions, offering better control over pH, viscosity, and metal ion removal.

The original patent disclosed stable oral suspensions of baclofen, but it had limitations in terms of pH control, viscosity, and metal ion removal. The present inventive concept solves these problems by introducing a system for stabilizing oral suspensions, a method for preparing stable suspensions, and a composition with improved viscosity and metal ion removal properties.

The inventive concept comprises a system for stabilizing oral suspensions of baclofen, which includes a container filled with a therapeutically effective amount of baclofen, a stabilizer dispenser that selectively releases at least one stabilizer, and a pH controller that adjusts the pH of the suspension to a predetermined range. The method for preparing a stable oral suspension involves mixing a therapeutically effective amount of baclofen with at least one stabilizer and adding a pH adjusting agent to achieve a pH between about 4 to about 8. The composition includes a therapeutically effective amount of baclofen, at least one stabilizer, and a viscosity modifier that maintains a predetermined viscosity over a range of temperatures.

The new claims introduce a novel system, method, and composition that overcome the limitations of the original patent. The inventive step lies in the integration of a stabilizer dispenser, pH controller, and viscosity modifier, which provides a more efficient, safer, and user-friendly solution for stable oral suspensions of baclofen.

Alternative embodiments of the inventive concept may include different types of containers, stabilizers, and pH controllers. Variations of the method may involve different mixing protocols, temperatures, and pH ranges. The composition may also be modified to include additional excipients or different viscosity modifiers.

The advanced stable oral suspensions of baclofen have significant commercial potential in the pharmaceutical industry, particularly in the treatment of spasticity, muscle spasms, and other conditions. The target market includes patients, caregivers, and healthcare professionals seeking more efficient, safer, and user-friendly solutions for baclofen administration.