Personalized Treatment of Surgery-Induced Cachexia through Advanced Immunonutrition

This invention provides a novel approach to preventing and treating surgery-induced cachexia through personalized immunonutrition supplements, leveraging genetic profiling, wearable devices, and delayed-release formulations to enhance treatment outcomes.

The original patent disclosed compositions and methods for treating or preventing surgery-induced cachexia and/or expression of myeloid-derived suppressor cells and pro-inflammatory cytokines. However, the original patent did not account for individual patient variability, leading to potential suboptimal treatment outcomes. The present inventive concept addresses this limitation by incorporating personalized dosing, real-time vital sign monitoring, and targeted formulations to ensure more effective and efficient treatment.

The new inventive concept comprises four main aspects: 1) personalized dosing of immunonutrition supplements based on a patient's genetic profile, 2) a wearable device that monitors vital signs and adjusts supplement dosing in real-time, 3) delayed-release formulations targeting the small intestine, and 4) combination therapy with probiotics. These advancements enable more precise and effective treatment of surgery-induced cachexia, reducing the risk of adverse reactions and improving patient outcomes.

The present inventive concept introduces novel elements not found in the original patent, including personalized dosing, wearable device-based monitoring, and delayed-release formulations. These advancements provide a significant improvement over existing treatments, offering a more tailored and efficient approach to preventing and treating surgery-induced cachexia.

Alternative embodiments may include using different biomarkers for personalized dosing, incorporating artificial intelligence in the wearable device, or developing new formulations targeting other areas of the gastrointestinal tract. These variations can help ensure broad conceptual coverage and adaptability to future advancements in the field.

This inventive concept has significant commercial potential in the healthcare and nutrition industries, particularly in the areas of surgical recovery, cancer treatment, and chronic disease management. The market for personalized nutrition and wearable devices is rapidly growing, and this invention is well-positioned to capitalize on these trends.