Synergistic Treatment and Prevention of Surgery-Induced Cachexia through AI-Powered Personalized Nutrition and Advanced Technologies

Publication ID: 24-11857525_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Treatment and Prevention of Surgery-Induced Cachexia through AI-Powered Personalized Nutrition and Advanced Technologies,” Published Technical Disclosure No. 24-11857525_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857525_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,525.

Summary of the Inventive Concept

The present disclosure relates to a comprehensive system for treating and preventing surgery-induced cachexia, leveraging synergistic combinations of AI, IoT, blockchain, and nanotechnology with specialized immunonutrition supplements to provide personalized and targeted interventions.

Background and Problem Solved

Surgery-induced cachexia is a severe and debilitating condition that affects millions of patients worldwide. The original patent disclosed compositions and methods for treating or preventing cachexia using specialized immunonutrition supplements. However, these approaches have limitations, such as lack of personalization, limited efficacy, and inadequate data management. The present inventive concept addresses these limitations by integrating advanced technologies to provide a more effective and comprehensive solution.

Detailed Description of the Inventive Concept

The system comprises a specialized immunonutrition supplement administered to a patient, which is combined with an AI-powered personalized nutrition planning module that generates a customized dietary plan based on the patient's genomic profile and medical history. Additionally, the system incorporates IoT-enabled sensors to track the patient's nutritional intake and physiological responses, which are integrated with a blockchain-based health record system to ensure secure and transparent data management. Furthermore, the system includes a composition for preventing or treating surgery-induced cachexia, comprising a synergistic blend of L-arginine, omega-3 fatty acids, and vitamin A, and a nanocarrier system for targeted delivery of the nutrients to the affected tissues.

Novelty and Inventive Step

The present inventive concept introduces a novel and non-obvious combination of AI, IoT, blockchain, and nanotechnology with specialized immunonutrition supplements, providing a synergistic and personalized approach to treating and preventing surgery-induced cachexia. The inventive concept's novelty lies in its ability to integrate multiple advanced technologies to provide a comprehensive solution that addresses the limitations of existing approaches.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include using machine learning algorithms to predict the risk of cachexia, or incorporating decentralized blockchain-based networks to share and analyze data from multiple healthcare providers. Variations of the composition may include different ratios of L-arginine, omega-3 fatty acids, and vitamin A, or the use of alternative nanocarrier systems.

Potential Commercial Applications and Market

The present inventive concept has significant commercial potential in the healthcare industry, particularly in the fields of oncology, surgery, and nutrition. The system's ability to provide personalized and targeted interventions makes it an attractive solution for healthcare providers and patients seeking more effective and efficient treatments for surgery-induced cachexia.

Original Patent Information

Patent NumberUS 11,857,525
TitleTreatment or prevention of surgery-induced cachexia and/or expression of myeloid-derived suppressor cells and pro-inflammatory cytokines
Assignee(s)SOCIÉTÉ DES PRODUITS NESTLÉ S.A.