Personalized Solriamfetol Therapy Systems with Integrated Technologies

Publication ID: 24-11857528_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Solriamfetol Therapy Systems with Integrated Technologies,” Published Technical Disclosure No. 24-11857528_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857528_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,528.

Summary of the Inventive Concept

The invention integrates solriamfetol therapy with AI, IoT, blockchain, and nano-particle technologies to provide personalized treatment for subjects with impaired renal function, enhancing efficacy and reducing adverse effects.

Background and Problem Solved

The original patent provides optimized dose escalation schemes for solriamfetol therapy in subjects with impaired renal function. However, these schemes have limitations in terms of individualized dosing and real-time monitoring. The new inventive concept addresses these limitations by incorporating advanced technologies to create a more effective and efficient treatment system.

Detailed Description of the Inventive Concept

The inventive concept comprises a wearable device for monitoring renal function, a blockchain-based database for storing patient data, and a machine learning algorithm for adjusting dosage based on individual patient response. The system may also utilize IoT-enabled devices for remote patient monitoring, AI-driven dosing optimization, and blockchain-based data security. Additionally, a novel nano-particle based delivery system can enhance bioavailability and reduce adverse effects. The personalized dosing platform utilizes machine learning to predict patient response, IoT-enabled devices for real-time monitoring, and blockchain-based data storage for secure patient records.

Novelty and Inventive Step

The new claims introduce the synergistic combination of solriamfetol therapy with AI, IoT, blockchain, and nano-particle technologies, which provides a non-obvious and innovative solution for personalized treatment of subjects with impaired renal function. The integration of these technologies enables real-time monitoring, individualized dosing, and enhanced efficacy, distinguishing the inventive concept from the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different AI algorithms, IoT devices, or blockchain platforms. Variations may include the integration of additional technologies, such as virtual or augmented reality, to enhance patient engagement and treatment outcomes.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the treatment of excessive daytime sleepiness and related disorders. The integration of advanced technologies can provide a competitive advantage in the market, and the personalized treatment approach can lead to improved patient outcomes and increased market share.

Original Patent Information

Patent NumberUS 11,857,528
TitleMethods of providing solriamfetol therapy to subjects with impaired renal function
Assignee(s)AXSOME MALTA LTD.