Personalized Cannabinoid Formulation System

Publication ID: 24-11857530_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Personalized Cannabinoid Formulation System,” Published Technical Disclosure No. 24-11857530_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857530_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,530.

Summary of the Inventive Concept

A system for tailoring cannabinoid formulations to individual genotypes, medical histories, and preferred cannabinoid ratios, ensuring optimal efficacy and minimizing adverse effects.

Background and Problem Solved

The original cannabinoid formulations patent (Cannabinoid formulations) has inherent limitations, including the lack of personalization and limited consideration of individual genetic variations. This inventive concept addresses these limitations by incorporating genetic profiling, formulation databases, and recommendation engines to provide personalized cannabinoid formulations.

Detailed Description of the Inventive Concept

The system consists of a genetic profiling module, a formulation database, and a recommendation engine. The genetic profiling module identifies an individual's genotype, focusing on polymorphisms relevant to cannabinoid metabolism and response. The formulation database contains a plurality of formulations with varying cannabinoid ratios, each optimized for specific genotypes and medical conditions. The recommendation engine selects a formulation based on the individual's genotype, medical history, and preferred cannabinoid ratio. The system can also adjust the formulation based on the individual's response to the formulation, ensuring optimal efficacy and minimizing adverse effects.

Novelty and Inventive Step

The new claims introduce a paradigm shift in cannabinoid formulations by incorporating genetic profiling, formulation databases, and recommendation engines. This personalized approach is non-obvious and novel compared to the original patent, which focused solely on cannabinoid ratios and terpene profiles.

Alternative Embodiments and Variations

Alternative embodiments may include the integration of artificial intelligence, machine learning algorithms, or blockchain technology to enhance the recommendation engine's accuracy and security. Variations may include the use of different genetic markers, additional cannabinoids, or alternative delivery methods.

Potential Commercial Applications and Market

The personalized cannabinoid formulation system has significant commercial potential in the medical cannabis industry, particularly in the areas of chronic pain management, anxiety treatment, and personalized medicine. The system can be marketed as a premium service, offering patients a tailored approach to cannabinoid therapy.

Field of Art

Pharmaceutical biotechnology, specifically cannabinoid formulation design and personalized medicine involving genetic profiling and drug composition optimization

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in pharmaceutical sciences, biotechnology, or pharmacogenomics, possessing expertise in cannabinoid pharmacology, genetic testing, and personalized medicine techniques

Obviousness Rationale

A PHOSITA would recognize that extending the source patent's cannabinoid formulation approach to include genetic profiling and personalized recommendation is a predictable application of known personalized medicine techniques. The source patent already establishes a foundation of tailored cannabinoid compositions, making the integration of genetic screening and recommendation algorithms a logical and incremental advancement. The technical elements of genotype-based formulation selection represent an obvious combination of existing pharmaceutical personalization strategies.

Obvious Combinations & Variations

Source Patent Element
Cannabinoid formulation with specific CBD:THC ratios and terpene profiles
PTD Variation
Adding genetic profiling module to select optimal cannabinoid ratios based on individual genotype
Obviousness Reasoning
Personalized medicine techniques routinely use genetic screening to optimize drug selection, making this extension a predictable application of known methodological approaches
Source Patent Element
Formulation comprising multiple cannabinoids and terpenes
PTD Variation
Creating a recommendation engine that dynamically adjusts formulation based on patient response
Obviousness Reasoning
Adaptive pharmaceutical systems are well-established, and applying this approach to cannabinoid formulations represents an obvious design choice for improving treatment outcomes
Source Patent Element
Cannabinoid composition with specific chemical ratios
PTD Variation
Developing a formulation database containing multiple cannabinoid ratio configurations
Obviousness Reasoning
Creating structured databases of pharmaceutical variations is a standard practice in drug development, making this systematic approach an obvious technical implementation
Source Patent Element
Cannabinoid formulation focused on specific medical applications
PTD Variation
Incorporating medical history into formulation recommendation process
Obviousness Reasoning
Integrating patient medical history into treatment selection is a standard practice in precision medicine, representing a predictable extension of existing pharmaceutical methodologies
Source Patent Element
Cannabinoid composition with defined terpene percentages
PTD Variation
Selecting terpene profiles based on genetic markers affecting cannabinoid metabolism
Obviousness Reasoning
Using genetic information to optimize drug composition is a known technique in pharmacogenomics, making this approach an obvious combination of existing scientific strategies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857530 and the disclosed personalized cannabinoid formulation system, a person of ordinary skill in the art would find the claimed variations obvious. The systematic integration of genetic profiling, formulation databases, and recommendation engines represents a predictable application of known personalized medicine techniques to cannabinoid composition design, thereby rendering subsequent claims of novelty invalid under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,530
TitleCannabinoid formulations
Assignee(s)Endocanna Health, Inc.