Personalized Cannabinoid Formulations via AI-driven Genetic Analysis

Publication ID: 24-11857530_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Cannabinoid Formulations via AI-driven Genetic Analysis,” Published Technical Disclosure No. 24-11857530_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857530_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,530.

Summary of the Inventive Concept

A next-generation system for tailored cannabinoid formulations using machine learning, genetic analysis, and real-time optimization to revolutionize individualized medicine.

Background and Problem Solved

The original patent disclosed cannabinoid formulations aligned with an individual's genotype based on a defined list of polymorphisms. However, this approach has limitations in terms of scalability, accuracy, and adaptability. The new inventive concept addresses these limitations by introducing AI-driven genetic analysis, real-time optimization, and personalized dosing, enabling a more precise and effective approach to cannabinoid therapy.

Detailed Description of the Inventive Concept

The system comprises a genetic analysis module, a formulation optimization module, and a manufacturing or dosing module. The genetic analysis module receives genomic data from a subject and generates a personalized cannabinoid profile. The formulation optimization module uses machine learning to optimize the cannabinoid ratios and terpene profiles based on the personalized profile. The manufacturing or dosing module produces or dispenses the optimized formulation in real-time. This integrated system enables personalized cannabinoid formulations that can adapt to an individual's unique genetic profile and environmental factors.

Novelty and Inventive Step

The new claims introduce a paradigm shift by incorporating AI-driven genetic analysis, machine learning, and real-time optimization to create personalized cannabinoid formulations. This approach is novel and non-obvious compared to the original patent, which relied on predefined polymorphisms and manual formulation optimization.

Alternative Embodiments and Variations

Alternative embodiments may include variations in the machine learning models, genetic analysis tools, and manufacturing or dosing methods. For example, the system could be integrated with wearable devices, mobile applications, or electronic health records to enhance user experience and data collection.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the personalized medicine and cannabis industries. Target markets may include pharmaceutical companies, dispensaries, and healthcare providers seeking to offer tailored cannabinoid therapies to patients. The system's adaptability and real-time optimization capabilities make it an attractive solution for addressing the complexities of individualized medicine.

Field of Art

Pharmaceutical biotechnology, specifically personalized medicine and cannabinoid formulation design, involving expertise in genomics, machine learning, pharmacogenomics, and pharmaceutical composition optimization

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in biotechnology, pharmacology, or biomedical engineering, possessing knowledge of genetic analysis, machine learning techniques, cannabinoid pharmacology, and personalized medicine approaches

Obviousness Rationale

The PTD represents a predictable technological progression from the source patent by applying established machine learning and genetic analysis techniques to the existing framework of personalized cannabinoid formulations. A PHOSITA would recognize that integrating AI-driven optimization with genetic profiling is a natural extension of the source patent's foundational approach of tailoring cannabinoid compositions to individual genetic characteristics. The technical implementation involves well-known computational methods and established personalized medicine paradigms that would be readily apparent to a skilled practitioner in the field.

Obvious Combinations & Variations

Source Patent Element
Cannabinoid formulations based on individual genotype polymorphisms
PTD Variation
AI-driven genetic analysis and machine learning for dynamic formulation optimization
Obviousness Reasoning
Applying computational optimization techniques to existing personalized medicine approaches represents a predictable technological improvement using known machine learning methodologies
Source Patent Element
Predefined cannabinoid and terpene ratios
PTD Variation
Real-time adaptive formulation based on genetic and environmental data
Obviousness Reasoning
Extending static formulation strategies to dynamic, data-driven approaches is an obvious design choice utilizing standard computational techniques in personalized medicine
Source Patent Element
Cannabinoid composition with specific CBD:THC ratios
PTD Variation
Machine learning models for predicting optimal cannabinoid ratios
Obviousness Reasoning
Implementing computational prediction models for pharmaceutical composition optimization is a well-established technique in pharmaceutical research with predictable and expected results
Source Patent Element
Genetic-based formulation design
PTD Variation
Integration with wearable devices and mobile applications for continuous monitoring
Obviousness Reasoning
Incorporating digital health technologies into personalized medicine approaches represents a standard technological progression with predictable implementation strategies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857530 and the published technical disclosure, a person of ordinary skill in the art would find the claimed personalized cannabinoid formulation system using AI-driven genetic analysis and machine learning optimization to be an obvious variation of the prior art. The disclosed system represents a straightforward application of known computational techniques to the existing framework of genotype-based cannabinoid formulation, thereby rendering such claims obvious under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,530
TitleCannabinoid formulations
Assignee(s)Endocanna Health, Inc.