Mast Cell Inhibition for Diverse Applications Beyond BPH/LUTS

Publication ID: 24-11857531_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Mast Cell Inhibition for Diverse Applications Beyond BPH/LUTS,” Published Technical Disclosure No. 24-11857531_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857531_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,531.

Summary of the Inventive Concept

This inventive concept leverages the core technology of mast cell inhibition to address unmet needs in agriculture, environmental sustainability, aquaculture, veterinary medicine, and human skin health, demonstrating its versatility and broad applicability.

Background and Problem Solved

The original patent focused on treating benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) using mast cell inhibition. However, the potential of this technology extends far beyond these specific applications. This inventive concept tackles the limitations of the original patent by exploring new use cases and industries where mast cell inhibition can provide significant benefits.

Detailed Description of the Inventive Concept

The new claims showcase the adaptability of mast cell inhibition in various contexts. For instance, in agriculture, mast cell stabilizers and histamine receptor antagonists can be used to prevent histamine release in response to pest allergens, reducing crop damage. In environmental sustainability, mast cell inhibitors and histamine receptor antagonists can mitigate the effects of climate change on pollinator populations. Similarly, in aquaculture, this composition can reduce inflammation and improve water quality. In veterinary medicine, the system can treat respiratory diseases in companion animals, and in human skin health, topical compositions can reduce inflammation and improve skin barrier function.

Novelty and Inventive Step

The novelty of this inventive concept lies in its application of mast cell inhibition to entirely new industries and problem domains. The inventive step is the recognition of the broader potential of this technology and its adaptation to address unmet needs in diverse fields.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept could include using different types of mast cell inhibitors or histamine receptor antagonists, varying the composition or dosage, or exploring other modes of administration. Additionally, the concept could be extended to other industries or applications, such as cosmetics, textiles, or biotechnology.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential across multiple industries, including agriculture, environmental sustainability, aquaculture, veterinary medicine, and human skin health. The market for these applications is substantial, with potential revenue streams from product sales, licensing, and partnerships.

Original Patent Information

Patent NumberUS 11,857,531
TitleCombination mast cell inhibition for treatment of BPH/LUTS
Assignee(s)Northwestern University