Synergistic Treatment System for Neurodegenerative Diseases

Publication ID: 24-11857534_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Treatment System for Neurodegenerative Diseases,” Published Technical Disclosure No. 24-11857534_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857534_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,534.

Summary of the Inventive Concept

A comprehensive system integrating Type I PRMT inhibitors with AI, IoT, and blockchain technologies to enhance treatment outcomes for ALS and FTD patients.

Background and Problem Solved

The original patent addressed the inhibition of dipeptide repeat proteins, but its limitations included the lack of a comprehensive system for diagnosing, treating, and tracking patient outcomes. The present inventive concept addresses this gap by integrating Type I PRMT inhibitors with advanced technologies to create a more effective and personalized treatment approach.

Detailed Description of the Inventive Concept

The system comprises a Type I PRMT inhibitor administration module, an AI-powered diagnostic module for identifying patients with ALS or FTD, and a blockchain-based data storage module for tracking patient treatment outcomes. The system may further include a wearable IoT device for monitoring patient motor neuron activity and transmitting data to the blockchain-based data storage module. The AI-powered predictive model analyzes patient data stored in the blockchain-based data storage module to predict treatment efficacy and identify novel biomarkers for ALS or FTD.

Novelty and Inventive Step

The new claims introduce the synergistic combination of Type I PRMT inhibitors with AI, IoT, and blockchain technologies, which is not obvious from the original patent. The inventive step lies in the integration of these distinct technologies to create a more powerful system for treating neurodegenerative diseases.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different AI algorithms, IoT devices, or blockchain platforms. Variations may include the integration of additional technologies, such as machine learning or natural language processing, to further enhance the system's capabilities.

Potential Commercial Applications and Market

The synergistic treatment system has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the areas of neurodegenerative disease treatment and personalized medicine. The system's ability to track patient outcomes and predict treatment efficacy makes it an attractive solution for pharmaceutical companies, hospitals, and research institutions.

Original Patent Information

Patent NumberUS 11,857,534
TitleInhibition of dipeptide repeat proteins
Assignee(s)ALS Therapy Development Institute