Glucokinase Activator-based Systems for Industrial, Agricultural, and Biotechnological Applications

Publication ID: 24-11857536_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Glucokinase Activator-based Systems for Industrial, Agricultural, and Biotechnological Applications,” Published Technical Disclosure No. 24-11857536_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857536_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,536.

Summary of the Inventive Concept

This inventive concept leverages the core technology of glucokinase activators to develop novel systems and methods for optimizing energy efficiency, enhancing crop yields, detecting kidney damage, treating muscle cramps, and improving microbial fuel cells.

Background and Problem Solved

The original patent focuses on treating diabetes with renal impairment using glucokinase activators. However, the potential of glucokinase activators extends beyond this specific application. This inventive concept addresses the limitation of the original patent by exploring new use cases in industries such as energy production, agriculture, biotechnology, and sports medicine.

Detailed Description of the Inventive Concept

The inventive concept comprises systems and methods that utilize glucokinase activators to achieve specific benefits in various industries. For instance, in industrial processes, glucokinase activators can optimize energy efficiency and reduce emissions. In agriculture, these activators can enhance crop yields in drought-prone regions by improving water use efficiency. In biotechnology, glucokinase activators can detect and prevent kidney damage in athletes, while in sports medicine, they can treat and prevent exercise-induced muscle cramps. Additionally, glucokinase activators can optimize energy production in microbial fuel cells.

Novelty and Inventive Step

The novelty of this inventive concept lies in the application of glucokinase activators to entirely new industries and use cases, which were not originally considered in the original patent. The inventive step is the recognition of the potential of glucokinase activators to address specific problems in these industries and the development of systems and methods to achieve these benefits.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept could include the use of different glucokinase activators, such as GKA-1, GKA-2, and GKA-3, or the development of new activators with improved properties. Variations could also include the integration of glucokinase activators with other technologies, such as IoT sensors or machine learning algorithms, to enhance their effectiveness.

Potential Commercial Applications and Market

The commercial potential of this inventive concept is significant, with potential applications in industries such as energy production, agriculture, biotechnology, and sports medicine. The target market includes companies and organizations operating in these industries, as well as research institutions and government agencies.

Original Patent Information

Patent NumberUS 11,857,536
TitleGlucokinase activator for treating diabetes with renal impairment
Assignee(s)HUA Medicine (Shanghai) Ltd.