Prostacyclin Antagonists for Agricultural Applications

Publication ID: 24-11857537_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Prostacyclin Antagonists for Agricultural Applications,” Published Technical Disclosure No. 24-11857537_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857537_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,537.

Summary of the Inventive Concept

Applying prostacyclin antagonists to agricultural fields to monitor and predict crop stress, optimize irrigation systems, detect soil moisture levels, enable precision farming, and reduce soil erosion.

Background and Problem Solved

The original patent disclosed the use of prostacyclin antagonists for treating ocular surface nociception. However, the agricultural industry faces significant challenges in optimizing crop management, conserving water resources, and mitigating soil erosion. The new inventive concept addresses these limitations by leveraging prostacyclin antagonists in novel agricultural applications.

Detailed Description of the Inventive Concept

The new inventive concept involves the use of prostacyclin antagonists in various agricultural applications. For instance, a system for monitoring and predicting crop stress can be developed by detecting chemical stimuli in soil using sensors and analyzing the data to alert farmers of potential crop stress. Similarly, prostacyclin antagonists can be used to optimize agricultural irrigation systems, detect soil moisture levels, enable precision farming, and reduce soil erosion. These applications take advantage of the unique properties of prostacyclin antagonists to interact with soil chemistry and provide valuable insights for farmers.

Novelty and Inventive Step

The new claims introduce a novel application of prostacyclin antagonists in the agricultural industry, which is non-obvious compared to the original patent's focus on ocular surface nociception. The inventive step lies in the recognition of the potential of prostacyclin antagonists to interact with soil chemistry and provide valuable insights for farmers.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of sensors, varying concentrations of prostacyclin antagonists, and integration with existing agricultural systems. Variations could also include the application of prostacyclin antagonists to different types of crops, soil conditions, and geographic regions.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in the agricultural industry, particularly in precision farming, irrigation management, and soil conservation. The target market includes farmers, agricultural companies, and organizations focused on sustainable agriculture and environmental conservation.

Field of Art

Pharmaceutical chemistry and agricultural biotechnology, with expertise in chemical compound interactions, sensor technologies, and biological signal detection systems

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degree in chemistry or biochemical engineering, familiar with compound interactions, sensor technologies, and cross-disciplinary applications of pharmaceutical compounds

Obviousness Rationale

A skilled practitioner would recognize that prostacyclin antagonists' chemical properties enable broad applications beyond their original medical context. The molecular mechanisms that interact with biological signaling pathways are transferable across different environmental systems. The PTD demonstrates a predictable extension of the source patent's compound characteristics by applying similar detection and interaction principles to agricultural monitoring.

Obvious Combinations & Variations

Source Patent Element
Topical administration of prostacyclin antagonists for detecting biological signals
PTD Variation
Using prostacyclin antagonists to detect chemical signals in soil environments
Obviousness Reasoning
Known technique of applying chemical sensors to detect biological interactions, with predictable results in alternative environmental contexts
Source Patent Element
Detecting nociceptive events on ocular surfaces
PTD Variation
Detecting stress signals in agricultural soil using similar chemical interaction principles
Obviousness Reasoning
Transferring signal detection methodologies from biological to agricultural systems represents an obvious design choice for a skilled practitioner
Source Patent Element
Pharmaceutical formulation of prostacyclin antagonists
PTD Variation
Developing agricultural formulations with similar compound concentrations and delivery mechanisms
Obviousness Reasoning
Adapting pharmaceutical formulation techniques to agricultural applications is a predictable engineering modification
Source Patent Element
Precise dosage and administration protocols
PTD Variation
Developing sensor-based application protocols for agricultural environments
Obviousness Reasoning
Extending precise administration techniques from medical to agricultural contexts represents a logical technological progression
Source Patent Element
Chemical compound interactions with biological systems
PTD Variation
Utilizing compound interactions to monitor and predict environmental conditions
Obviousness Reasoning
Applying known chemical interaction principles to alternative diagnostic contexts is an obvious technological extension
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857537 and the disclosed agricultural applications, a person having ordinary skill in the art would find the proposed variations obvious, as the fundamental chemical interaction principles and detection methodologies are substantially similar across biological and environmental systems, thereby rendering subsequent claims obvious as a matter of routine scientific and engineering design.

Original Patent Information

Patent NumberUS 11,857,537
TitleUse of prostacyclin antagonists for treating ocular surface nociception
Assignee(s)JENIVISION INC.