Synergistic Ocular Pain Management System

Publication ID: 24-11857537_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Ocular Pain Management System,” Published Technical Disclosure No. 24-11857537_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857537_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,537.

Summary of the Inventive Concept

The present inventive concept integrates prostacyclin antagonists with advanced technologies, such as AI, IoT, blockchain, and novel materials, to create a comprehensive system for treating and managing ocular pain, offering enhanced efficacy, personalized treatment, and improved patient outcomes.

Background and Problem Solved

The original patent disclosed the use of prostacyclin antagonists for treating ocular surface nociception. However, the existing approaches lack the ability to provide personalized treatment regimens, real-time monitoring, and secure data tracking. The present inventive concept addresses these limitations by combining the prostacyclin antagonists with cutting-edge technologies to create a more powerful and effective system.

Detailed Description of the Inventive Concept

The synergistic ocular pain management system comprises a prostacyclin antagonist, an AI-powered diagnostic module, a blockchain-secured platform, and IoT-enabled communication modules. The system enables personalized treatment regimens based on patient-specific data, real-time monitoring of ocular surface nociception, and secure tracking of patient responses to therapy. The system can be integrated with wearable devices, novel material compositions for ocular implants, and smart contact lenses to provide a comprehensive solution for ocular pain management.

Novelty and Inventive Step

The present inventive concept introduces a novel combination of prostacyclin antagonists with advanced technologies, providing a synergistic effect that enhances the efficacy and personalization of ocular pain treatment. The integration of AI, IoT, blockchain, and novel materials with prostacyclin antagonists is new and non-obvious compared to the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include integrating the prostacyclin antagonists with other technologies, such as machine learning algorithms, virtual reality, or 3D printing. Variations of the system could be designed for specific ocular conditions, such as dry eye disease or glaucoma, or for use in different patient populations, such as pediatric or geriatric patients.

Potential Commercial Applications and Market

The synergistic ocular pain management system has significant commercial potential in the ophthalmology and healthcare industries. The system could be marketed to pharmaceutical companies, medical device manufacturers, and healthcare providers, offering a comprehensive solution for ocular pain management and improved patient outcomes.

Original Patent Information

Patent NumberUS 11,857,537
TitleUse of prostacyclin antagonists for treating ocular surface nociception
Assignee(s)JENIVISION INC.