Specialized Ocular Pain Management Systems for Niche Environments

Publication ID: 24-11857537_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Ocular Pain Management Systems for Niche Environments,” Published Technical Disclosure No. 24-11857537_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857537_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,537.

Summary of the Inventive Concept

The present inventive concept relates to the development of specialized systems and methods for treating ocular pain in high-altitude environments, extreme temperatures, emergency response situations, and individuals with compromised immune systems or a history of eye trauma.

Background and Problem Solved

The original patent disclosed the use of prostacyclin antagonists for treating ocular surface nociception. However, it did not address the specific challenges and requirements of treating ocular pain in unique operational environments. The present inventive concept addresses these limitations by providing tailored solutions for niche markets, ensuring effective and safe treatment of ocular pain in these environments.

Detailed Description of the Inventive Concept

The inventive concept comprises systems and methods for treating ocular pain in high-altitude environments, extreme temperatures, emergency response situations, and individuals with compromised immune systems or a history of eye trauma. These systems and methods utilize 4,5-dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imadazol-2-amine or a pharmaceutically acceptable salt thereof, and may include additional components such as portable oxygen supplies, pressurized containers, protective eyewear, sterilization modules, and protective eye shields. The systems and methods are designed to provide effective and safe treatment of ocular pain in these unique environments, taking into account the specific challenges and requirements of each niche market.

Novelty and Inventive Step

The present inventive concept is novel and non-obvious over the original patent because it provides specialized systems and methods for treating ocular pain in niche environments, which were not addressed by the original patent. The inventive concept's combination of 4,5-dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imadazol-2-amine or a pharmaceutically acceptable salt thereof with additional components and features tailored to each niche market constitutes an inventive step.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include the use of different prostacyclin antagonists or formulations, alternative delivery methods or devices, and additional components or features tailored to specific niche markets. Variations of the inventive concept may also include the use of different types of protective eyewear or sterilization modules, or the integration of the systems and methods with existing medical devices or equipment.

Potential Commercial Applications and Market

The present inventive concept has significant commercial potential in various industries, including aerospace, emergency response, healthcare, and extreme sports. The market for specialized ocular pain management systems is growing, driven by the increasing need for effective and safe treatment of ocular pain in unique operational environments. The inventive concept's ability to address the specific challenges and requirements of these niche markets positions it for significant market share and revenue growth.

Original Patent Information

Patent NumberUS 11,857,537
TitleUse of prostacyclin antagonists for treating ocular surface nociception
Assignee(s)JENIVISION INC.