Personalized Ocular Pain Management System
Legal Citation
Summary of the Inventive Concept
A next-generation system for personalized ocular pain management, integrating wearable sensors, micro-dosing devices, and AI-driven analytics to provide targeted and sustained relief from ocular pain.
Background and Problem Solved
The original patent disclosed the use of prostacyclin antagonists for treating ocular surface nociception, but it had limitations in terms of personalized treatment and real-time monitoring. The present inventive concept addresses these limitations by introducing a wearable sensor and micro-dosing device that work in tandem to detect and respond to ocular surface nociception in real-time, providing a more effective and personalized treatment approach.
Detailed Description of the Inventive Concept
The system comprises a portable, wearable sensor that detects changes in ocular surface nociception and transmits data to a micro-dosing device, which delivers a tailored amount of a prostacyclin antagonist to the affected eye. The system can be integrated with AI-driven analytics to predict and prevent ocular pain, and can be used in conjunction with novel formulations of prostacyclin antagonists that release the antagonist in response to changes in ocular surface pH. Additionally, the system can be expanded to include smart contact lenses and neural interfaces that provide real-time relief from ocular discomfort.
Novelty and Inventive Step
The present inventive concept introduces a novel combination of wearable sensors, micro-dosing devices, and AI-driven analytics to provide personalized ocular pain management, which is not disclosed in the original patent. The use of wearable sensors and micro-dosing devices to detect and respond to ocular surface nociception in real-time is a significant departure from the original patent's approach, and the integration of AI-driven analytics provides an additional layer of sophistication and personalization.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different types of sensors, such as electroencephalography (EEG) or functional near-infrared spectroscopy (fNIRS), to detect changes in ocular surface nociception. The system could also be adapted for use in veterinary medicine, or integrated with other therapeutic modalities, such as electrical stimulation or phototherapy, to provide a more comprehensive treatment approach.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential in the ophthalmic industry, with potential applications in the treatment of dry eye disease, ocular surface injuries, and other conditions characterized by ocular pain. The system's ability to provide personalized and targeted relief from ocular pain could make it an attractive option for patients and clinicians alike, and its potential integration with AI-driven analytics could provide a competitive advantage in the market.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Ophthalmology and pharmaceutical drug delivery, specifically focused on ocular surface pain management and targeted drug delivery systems for treating dry eye disease and nociception
Person of Ordinary Skill (PHOSITA) Profile
A medical researcher or pharmaceutical engineer with expertise in ophthalmology, drug formulation, medical device design, and sensor technologies, holding advanced degrees in biomedical engineering, pharmacology, or related fields
Obviousness Rationale
A person of ordinary skill would recognize that the PTD's personalized ocular pain management system represents a predictable technological evolution of the source patent's prostacyclin antagonist treatment method. The integration of wearable sensors, micro-dosing devices, and AI-driven analytics provides a natural extension of the original patent's therapeutic approach by enhancing targeted drug delivery and real-time monitoring of ocular surface conditions. The technical variations demonstrate incremental improvements using known technologies and design principles within the field of ocular therapeutics.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,537 |
|---|---|
| Title | Use of prostacyclin antagonists for treating ocular surface nociception |
| Assignee(s) | JENIVISION INC. |