Pilocarpine-based compositions for non-ophthalmic applications
Legal Citation
Summary of the Inventive Concept
This inventive concept explores novel applications of pilocarpine-based compositions beyond ophthalmic uses, leveraging the core technology's stability and versatility to address various industrial and environmental challenges.
Background and Problem Solved
The original patent focused on treating ophthalmic conditions, but its buffer characteristics and pH stability have broader implications. This inventive concept tackles the limitations of the original patent by applying the core technology to new areas, such as environmental humidity control, food preservation, fungal growth control, textile treatment, and pest population management.
Detailed Description of the Inventive Concept
The new claims describe systems, methods, and devices that utilize pilocarpine-based compositions to modulate humidity levels, preserve food products, control fungal growth, treat textiles, and manage pest populations. These compositions maintain a pH of between about 3 and about 6 and at least about 97% of the pilocarpine compound originally present when stored under specific conditions. The inventive concept's components and operation involve integrating the pilocarpine-based composition with sensing, application, or control means to achieve the desired outcome in each respective field.
Novelty and Inventive Step
The novelty of this inventive concept lies in the unexpected application of pilocarpine-based compositions to non-ophthalmic areas, which was not obvious from the original patent. The inventive step involves recognizing the versatility of the core technology and adapting it to address specific challenges in various industries.
Alternative Embodiments and Variations
Alternative embodiments may include using different pilocarpine salts or varying the buffer content to optimize performance in specific applications. Variations could involve combining the pilocarpine-based composition with other active ingredients or adjusting the pH range to accommodate different environmental conditions.
Potential Commercial Applications and Market
This inventive concept has significant commercial potential in industries such as agriculture, textiles, construction, and environmental monitoring. The market demand for innovative solutions in these areas is substantial, and the pilocarpine-based compositions' stability and versatility make them attractive candidates for further development and commercialization.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical and chemical engineering, with expertise in composition formulation, drug delivery systems, and material science applications, particularly focused on pilocarpine-based compositions and their potential industrial uses
Person of Ordinary Skill (PHOSITA) Profile
A professional with advanced degree in chemistry or pharmaceutical sciences, experienced in formulation development, familiar with drug stability principles, and capable of identifying potential cross-disciplinary applications of pharmaceutical compounds
Obviousness Rationale
A PHOSITA would recognize that the stable pilocarpine composition disclosed in the source patent inherently possesses properties that enable broader applications beyond ophthalmic use. The consistent pH stability, low buffer content, and predictable compound characteristics suggest potential utility in various environmental and industrial contexts. The technical variations proposed in the PTD represent logical extensions of the original composition's fundamental properties.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,538 |
|---|---|
| Title | Stable pilocarpine formulations with modified buffer characteristics and related methods |
| Assignee(s) | Somerset Therapeutics, LLC |