Pilocarpine-based compositions for non-ophthalmic applications

Publication ID: 24-11857538_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Pilocarpine-based compositions for non-ophthalmic applications,” Published Technical Disclosure No. 24-11857538_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857538_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,538.

Summary of the Inventive Concept

This inventive concept explores novel applications of pilocarpine-based compositions beyond ophthalmic uses, leveraging the core technology's stability and versatility to address various industrial and environmental challenges.

Background and Problem Solved

The original patent focused on treating ophthalmic conditions, but its buffer characteristics and pH stability have broader implications. This inventive concept tackles the limitations of the original patent by applying the core technology to new areas, such as environmental humidity control, food preservation, fungal growth control, textile treatment, and pest population management.

Detailed Description of the Inventive Concept

The new claims describe systems, methods, and devices that utilize pilocarpine-based compositions to modulate humidity levels, preserve food products, control fungal growth, treat textiles, and manage pest populations. These compositions maintain a pH of between about 3 and about 6 and at least about 97% of the pilocarpine compound originally present when stored under specific conditions. The inventive concept's components and operation involve integrating the pilocarpine-based composition with sensing, application, or control means to achieve the desired outcome in each respective field.

Novelty and Inventive Step

The novelty of this inventive concept lies in the unexpected application of pilocarpine-based compositions to non-ophthalmic areas, which was not obvious from the original patent. The inventive step involves recognizing the versatility of the core technology and adapting it to address specific challenges in various industries.

Alternative Embodiments and Variations

Alternative embodiments may include using different pilocarpine salts or varying the buffer content to optimize performance in specific applications. Variations could involve combining the pilocarpine-based composition with other active ingredients or adjusting the pH range to accommodate different environmental conditions.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential in industries such as agriculture, textiles, construction, and environmental monitoring. The market demand for innovative solutions in these areas is substantial, and the pilocarpine-based compositions' stability and versatility make them attractive candidates for further development and commercialization.

Original Patent Information

Patent NumberUS 11,857,538
TitleStable pilocarpine formulations with modified buffer characteristics and related methods
Assignee(s)Somerset Therapeutics, LLC