Personalized Dyslipidemia Treatment Systems via Synergistic Combinations

Publication ID: 24-11857540_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Dyslipidemia Treatment Systems via Synergistic Combinations,” Published Technical Disclosure No. 24-11857540_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857540_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,540.

Summary of the Inventive Concept

Integrating pemafibrate dosing regimens with AI, IoT, blockchain, and novel materials to create a more effective and personalized treatment system for dyslipidemia

Background and Problem Solved

The original pemafibrate dosing regimens, while effective, have limitations in terms of individual patient responses and treatment outcomes. This new inventive concept addresses these limitations by combining pemafibrate with distinct technologies to create a more powerful and personalized treatment system.

Detailed Description of the Inventive Concept

The new inventive concept comprises a pemafibrate dosing regimen module integrated with an AI-powered patient data analytics platform to optimize pemafibrate dosage based on individual patient responses. Additionally, IoT-enabled wearable devices and machine learning algorithms are used for real-time monitoring of pemafibrate efficacy. A blockchain-based secure data storage system is employed for pemafibrate treatment outcomes, enabling secure sharing of patient data with healthcare providers and researchers. Furthermore, a pemafibrate-based pharmaceutical composition incorporating a novel, biodegradable material for sustained release of pemafibrate is used. A machine learning model trained on a dataset of OATP1B inhibitor interactions is used to predict pemafibrate-drug interactions, enabling personalized medicine.

Novelty and Inventive Step

The new inventive concept's integration of pemafibrate dosing regimens with AI, IoT, blockchain, and novel materials constitutes a non-obvious and novel combination that provides a more effective and personalized treatment system for dyslipidemia. The use of machine learning algorithms, blockchain, and novel materials in this context is particularly innovative and provides a significant improvement over the original pemafibrate dosing regimens.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT devices, or blockchain platforms. Additionally, the pemafibrate-based pharmaceutical composition could be modified to incorporate different biodegradable materials or release mechanisms. The machine learning model could be trained on different datasets or used in conjunction with other predictive analytics tools.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the area of personalized medicine. The target market includes healthcare providers, researchers, and patients with dyslipidemia. The inventive concept's ability to provide more effective and personalized treatment outcomes could lead to increased adoption and market share.

Original Patent Information

Patent NumberUS 11,857,540
TitlePemafibrate dosing regimens
Assignee(s)KOWA COMPANY, LTD.