FLT3 Mutation-Based Solutions for Industrial, Agricultural, and Environmental Applications

Publication ID: 24-11857546_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “FLT3 Mutation-Based Solutions for Industrial, Agricultural, and Environmental Applications,” Published Technical Disclosure No. 24-11857546_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857546_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,546.

Summary of the Inventive Concept

This inventive concept leverages the core technology of crenolanib to address novel applications in industrial air quality control, agricultural fungal infection prevention, water contamination removal, veterinary disease treatment, and pest population management.

Background and Problem Solved

The original patent focused on treating FLT3 mutated proliferative disorders in humans. However, the limitations of this approach lie in its narrow scope and lack of consideration for other industries and fields where FLT3 mutations could be exploited. This inventive concept addresses these limitations by applying the core technology to entirely new domains.

Detailed Description of the Inventive Concept

The inventive concept comprises novel systems and methods that utilize crenolanib or its salts to target FLT3 mutated particles, fungal strains, contaminants, pathogens, or pest populations in various industries. For instance, the air quality monitoring system detects FLT3 mutated particles and employs a crenolanib-based air purification unit to reduce their presence. Similarly, the agricultural fungicide applies a crenolanib-based solution to target FLT3 mutated fungal strains, preventing crop infections. The water supply system detects and removes FLT3 mutated contaminants using a crenolanib-based detection unit and removal unit. The veterinary therapeutic administers a crenolanib-based treatment to animals infected with FLT3 mutated pathogens. Lastly, the pest population management system monitors and controls FLT3 mutated pest populations in agricultural fields using a crenolanib-based detection unit and population control unit.

Novelty and Inventive Step

The novelty of this inventive concept lies in its application of crenolanib to entirely new industries and fields, which was not considered in the original patent. The inventive step is the recognition of the potential of crenolanib to address FLT3 mutations in these novel contexts, leading to the development of innovative systems and methods that provide significant benefits over existing solutions.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept could include the use of different detection methods, varying concentrations of crenolanib, or combinations with other therapeutic agents. Variations could also involve adapting the systems and methods for use in other industries or fields where FLT3 mutations are relevant.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential in various industries, including industrial air quality control, agricultural fungicides, water treatment, veterinary therapeutics, and pest population management. The target market includes companies and organizations operating in these industries, as well as government agencies responsible for environmental regulation and public health.

Original Patent Information

Patent NumberUS 11,857,546
TitleCrenolanib for treating FLT3 mutated proliferative disorders relapsed/refractory to prior treatment
Assignee(s)Arog Pharmaceuticals, Inc.