FLT3 Inhibitor-Based Agricultural Pest Control Systems and Methods

Publication ID: 24-11857546_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “FLT3 Inhibitor-Based Agricultural Pest Control Systems and Methods,” Published Technical Disclosure No. 24-11857546_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857546_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,546.

Summary of the Inventive Concept

The present inventive concept relates to the application of crenolanib, or salts thereof, to control and monitor FLT3 mutated pest populations in agricultural settings, providing a novel approach to pest management and reducing the environmental impact of traditional pest control methods.

Background and Problem Solved

The original patent disclosed the use of crenolanib for treating FLT3 mutated proliferative disorders in humans. However, the problem of FLT3 mutated pest populations in agricultural settings remains unsolved. The present inventive concept addresses this limitation by applying the core technology of the original patent to a new field, providing a targeted and effective solution for pest control and monitoring.

Detailed Description of the Inventive Concept

The inventive concept comprises systems and methods for detecting and controlling FLT3 mutated pest populations using crenolanib or its pharmaceutically acceptable salts. The system includes a sensor for detecting FLT3 mutated pest populations and a dispenser for releasing a therapeutically effective amount of crenolanib to treat the pest populations. The method involves applying a composition comprising crenolanib to the crops and monitoring the crops for signs of pest infestation. Additionally, the inventive concept includes a device for detecting FLT3 mutated pests and a system for reducing the environmental impact of agricultural pest control.

Novelty and Inventive Step

The new claims are novel and non-obvious over the original patent as they apply the FLT3 inhibitor technology to a completely new field, agricultural pest control, and provide a targeted solution for controlling FLT3 mutated pest populations. The inventive concept's novelty lies in the unexpected application of crenolanib to agricultural pest control, which is not suggested by the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept include using different FLT3 inhibitors, varying the composition and dosage of crenolanib, and integrating the system with existing agricultural monitoring and control systems. Variations of the method include using different application methods, such as spraying or injection, and combining crenolanib with other pest control agents.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the agricultural industry, particularly in the areas of pest control and crop protection. The target market includes agricultural companies, farmers, and crop protection services. The inventive concept's environmental benefits and targeted approach to pest control make it an attractive solution for the agricultural industry.

Original Patent Information

Patent NumberUS 11,857,546
TitleCrenolanib for treating FLT3 mutated proliferative disorders relapsed/refractory to prior treatment
Assignee(s)Arog Pharmaceuticals, Inc.