FLT3 Inhibitor-Based Agricultural Pest Control Systems and Methods
Legal Citation
Summary of the Inventive Concept
The present inventive concept relates to the application of crenolanib, or salts thereof, to control and monitor FLT3 mutated pest populations in agricultural settings, providing a novel approach to pest management and reducing the environmental impact of traditional pest control methods.
Background and Problem Solved
The original patent disclosed the use of crenolanib for treating FLT3 mutated proliferative disorders in humans. However, the problem of FLT3 mutated pest populations in agricultural settings remains unsolved. The present inventive concept addresses this limitation by applying the core technology of the original patent to a new field, providing a targeted and effective solution for pest control and monitoring.
Detailed Description of the Inventive Concept
The inventive concept comprises systems and methods for detecting and controlling FLT3 mutated pest populations using crenolanib or its pharmaceutically acceptable salts. The system includes a sensor for detecting FLT3 mutated pest populations and a dispenser for releasing a therapeutically effective amount of crenolanib to treat the pest populations. The method involves applying a composition comprising crenolanib to the crops and monitoring the crops for signs of pest infestation. Additionally, the inventive concept includes a device for detecting FLT3 mutated pests and a system for reducing the environmental impact of agricultural pest control.
Novelty and Inventive Step
The new claims are novel and non-obvious over the original patent as they apply the FLT3 inhibitor technology to a completely new field, agricultural pest control, and provide a targeted solution for controlling FLT3 mutated pest populations. The inventive concept's novelty lies in the unexpected application of crenolanib to agricultural pest control, which is not suggested by the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept include using different FLT3 inhibitors, varying the composition and dosage of crenolanib, and integrating the system with existing agricultural monitoring and control systems. Variations of the method include using different application methods, such as spraying or injection, and combining crenolanib with other pest control agents.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the agricultural industry, particularly in the areas of pest control and crop protection. The target market includes agricultural companies, farmers, and crop protection services. The inventive concept's environmental benefits and targeted approach to pest control make it an attractive solution for the agricultural industry.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical and biotechnology research, specifically targeting kinase inhibitors and their potential applications in therapeutic and agricultural domains
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in molecular biology, pharmacology, or biochemistry, possessing expertise in kinase inhibition, drug repurposing, and cross-domain technology translation
Obviousness Rationale
A PHOSITA would recognize that the fundamental mechanism of FLT3 inhibition disclosed in the source patent could be readily adapted to alternative domains like pest control, given the structural similarities between cellular signaling pathways in human and agricultural systems. The technical principles of targeted molecular intervention are transferable across biological contexts, making the agricultural pest control application a predictable extension of the original therapeutic approach.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,546 |
|---|---|
| Title | Crenolanib for treating FLT3 mutated proliferative disorders relapsed/refractory to prior treatment |
| Assignee(s) | Arog Pharmaceuticals, Inc. |