Crenolanib-based Solutions for Specialized Treatment Environments

Publication ID: 24-11857546_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Crenolanib-based Solutions for Specialized Treatment Environments,” Published Technical Disclosure No. 24-11857546_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857546_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,546.

Summary of the Inventive Concept

The present invention provides novel crenolanib-based systems, methods, and compositions tailored for treating FLT3 mutated proliferative disorders in high-security facilities, disaster relief settings, extreme weather conditions, remote or isolated locations, and areas with limited access to medical facilities.

Background and Problem Solved

The original patent disclosed the use of crenolanib for treating FLT3 mutated proliferative disorders. However, the existing solutions do not adequately address the unique challenges and constraints of specialized treatment environments. The present inventive concept addresses these limitations by providing targeted solutions for specific operational environments, ensuring effective treatment and improved patient outcomes.

Detailed Description of the Inventive Concept

The inventive concept encompasses a range of novel systems, methods, and compositions that adapt crenolanib-based treatment to distinct operational environments. For instance, the system for high-security facilities features a secure storage unit, dispensing unit, and monitoring unit to ensure controlled and monitored treatment. The method for disaster relief settings involves administering crenolanib through a portable, self-contained treatment unit. The composition for extreme weather conditions incorporates weather-resistant packaging to protect the formulation from environmental degradation. The kit for remote or isolated locations includes instructional materials and a container holding a therapeutically effective amount of crenolanib. The system for areas with limited access to medical facilities leverages telemedicine and remote dispensing units to facilitate treatment.

Novelty and Inventive Step

The inventive concept's novelty lies in its tailored approach to addressing the specific challenges of specialized treatment environments. The new claims introduce non-obvious features, such as secure storage units, portable treatment units, weather-resistant packaging, and remote dispensing units, which differentiate the inventive concept from the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include modifying the dispensing unit for high-security facilities to accommodate varying levels of security clearance. Variations of the method for disaster relief settings could involve integrating the portable treatment unit with existing emergency response systems. Other embodiments might focus on adapting the composition for extreme weather conditions to specific environmental stressors, such as high temperatures or humidity.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the areas of oncology and rare disease treatment. Target markets include government agencies, disaster relief organizations, and healthcare providers operating in specialized environments. The inventive concept's tailored solutions can improve patient outcomes, reduce treatment costs, and enhance the overall efficiency of healthcare services in these unique settings.

Original Patent Information

Patent NumberUS 11,857,546
TitleCrenolanib for treating FLT3 mutated proliferative disorders relapsed/refractory to prior treatment
Assignee(s)Arog Pharmaceuticals, Inc.