Synergistic Opioid Overdose Rescue Systems

Publication ID: 24-11857547_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Opioid Overdose Rescue Systems,” Published Technical Disclosure No. 24-11857547_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857547_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,547.

Summary of the Inventive Concept

Integrating opioid antagonist delivery with AI, IoT, blockchain, and novel materials to create more effective and personalized opioid overdose rescue systems

Background and Problem Solved

The original patent addressed the need for effective opioid overdose rescue, but its limitations include lack of personalized detection, delayed response, and limited therapeutic efficacy. The new inventive concept addresses these limitations by combining opioid antagonist delivery with advanced technologies to provide real-time detection, rapid response, and enhanced therapeutic outcomes

Detailed Description of the Inventive Concept

The new inventive concept comprises a system for opioid overdose rescue, integrating an opioid antagonist delivery device with an AI-powered sensor for detecting opioid exposure. The sensor triggers the delivery device to administer a therapeutically effective amount of the opioid antagonist. Additionally, the system may include a blockchain-based reward system to incentivize subjects to maintain abstinence from opioids, or a nanocarrier-based delivery system for targeted opioid receptor binding. The system may also incorporate an IoT-enabled tracking device for monitoring vital signs and an AI-powered predictive model for predicting opioid overdose risk

Novelty and Inventive Step

The new claims introduce the concept of integrating opioid antagonist delivery with AI, IoT, blockchain, and novel materials, which is not obvious from the original patent. The inventive step lies in the synergistic combination of these technologies to create a more effective and personalized opioid overdose rescue system

Alternative Embodiments and Variations

Alternative embodiments may include using different AI algorithms, varying the type of IoT-enabled tracking device, or incorporating additional novel materials for enhanced therapeutic efficacy. Variations may also include adapting the system for use in different settings, such as emergency response or clinical treatment

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the opioid overdose rescue market, with potential applications in emergency response, clinical treatment, and public health initiatives. The target industries include pharmaceutical companies, medical device manufacturers, and healthcare providers

Original Patent Information

Patent NumberUS 11,857,547
TitleCompositions and methods for opioid antagonist delivery
Assignee(s)Purdue Pharma L.P.