Adaptable Opioid Antagonist Delivery Systems for Specialized Environments
Legal Citation
Summary of the Inventive Concept
The present inventive concept relates to specialized variations of opioid antagonist delivery systems, tailored to address specific operational environments, such as high-security needs, disaster relief, extreme weather conditions, and remote areas.
Background and Problem Solved
The original patent disclosed compositions and methods for opioid antagonist delivery, providing a solution for rescuing a subject from an opioid overdose. However, these solutions may not be suitable for specific, narrow market segments or unique operational environments. The present inventive concept addresses this limitation by adapting the opioid antagonist delivery system for these specialized environments, ensuring effective and timely rescue in diverse scenarios.
Detailed Description of the Inventive Concept
The inventive concept comprises a range of adaptations to the original opioid antagonist delivery system, including portable, tamper-evident containers for high-security environments; formulations and administration methods tailored for disaster relief settings; and specialized packaging and delivery systems for extreme weather conditions and remote areas. These adaptations enable the effective delivery of opioid antagonists in a variety of challenging environments, ensuring timely rescue and treatment.
Novelty and Inventive Step
The present inventive concept introduces novel adaptations to the original opioid antagonist delivery system, providing a non-obvious solution for addressing specific operational environments. The combination of portable containers, specialized formulations, and tailored administration methods constitutes a new and inventive approach to opioid antagonist delivery.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include variations in container design, formulation composition, and administration methods. For example, the use of biodegradable materials for containers, or the incorporation of additional therapeutic agents to address co-occurring conditions. These variations ensure broad conceptual coverage and adaptability to diverse operational environments.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential in the pharmaceutical and biotechnology industries, particularly in the areas of emergency response, disaster relief, and specialized healthcare services. The targeted market segments include government agencies, non-profit organizations, and private companies operating in high-security, disaster relief, and remote areas.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical formulations, specifically opioid antagonist delivery systems, with expertise in parenteral drug delivery, pharmacokinetics, and medical emergency interventions
Person of Ordinary Skill (PHOSITA) Profile
A pharmaceutical scientist or pharmacologist with advanced degree, experience in drug formulation, understanding of parenteral delivery techniques, knowledge of adjuvant interactions, and familiarity with specialized medical environments
Obviousness Rationale
A PHOSITA would recognize that adapting the nalmefene parenteral formulation to specialized environments represents predictable variations using known pharmaceutical engineering techniques. The core pharmacological mechanism remains consistent across the disclosed variations, with container and delivery method modifications being routine design choices. The source patent's fundamental formulation provides a clear technical foundation that enables straightforward adaptation to different operational contexts.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,547 |
|---|---|
| Title | Compositions and methods for opioid antagonist delivery |
| Assignee(s) | Purdue Pharma L.P. |