Opioid Overdose Rescue and Prevention System
Legal Citation
Summary of the Inventive Concept
A comprehensive system for opioid overdose rescue and prevention, leveraging the core technology of the original patent to address the opioid epidemic through innovative applications and use cases.
Background and Problem Solved
The original patent relates to pharmaceutical compositions for rescuing a subject from an opioid overdose. However, the opioid epidemic requires a more comprehensive approach, including detection, treatment, and prevention. The new inventive concept addresses these limitations by applying the core technology to entirely new fields, such as wearable sensors, mobile applications, and population monitoring.
Detailed Description of the Inventive Concept
The system comprises a wearable sensor that detects opioid overdose in a subject, triggering a mobile application to alert emergency services. Additionally, the system includes a portable device for opioid overdose rescue, containing a parenteral formulation according to the original patent and an instructional module. Furthermore, the system features a population monitoring component, utilizing a database of opioid prescriptions and a machine learning algorithm to identify high-risk individuals and alert healthcare providers. The system also encompasses a method for treating opioid withdrawal, combining the opioid antagonist formulation with cognitive behavioral therapy.
Novelty and Inventive Step
The new claims introduce entirely novel applications and use cases for the core technology, including wearable sensors, mobile applications, and population monitoring. These innovations provide a non-obvious solution to the opioid epidemic, addressing the limitations of the original patent and expanding its reach to new fields.
Alternative Embodiments and Variations
Alternative embodiments may include integrating the wearable sensor with other health monitoring devices, developing a virtual reality platform for cognitive behavioral therapy, or incorporating artificial intelligence into the population monitoring component. Variations may include adapting the system for use in different demographics or geographic regions.
Potential Commercial Applications and Market
The Opioid Overdose Rescue and Prevention System has significant commercial potential in the healthcare and pharmaceutical industries, targeting markets such as emergency medical services, substance abuse treatment centers, and healthcare providers. The system's innovative approach to addressing the opioid epidemic positions it for widespread adoption and significant revenue growth.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical formulations, medical device systems, and opioid antagonist delivery technologies, requiring advanced knowledge in pharmacology, medical device design, and clinical intervention strategies
Person of Ordinary Skill (PHOSITA) Profile
A professional with advanced degrees in pharmaceutical sciences or biomedical engineering, experienced in drug delivery systems, medical device development, and clinical intervention technologies, with expertise in opioid pharmacology and emergency medical response
Obviousness Rationale
A PHOSITA would recognize that the source patent's nalmefene formulation provides a foundational technology that can be readily extended into comprehensive overdose prevention and intervention systems. The technical principles of rapid opioid antagonist delivery inherently suggest broader applications in emergency response, patient monitoring, and public health interventions. The disclosed variations represent predictable combinations of known medical technologies that would be obvious to implement given the existing pharmaceutical and medical device knowledge.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,547 |
|---|---|
| Title | Compositions and methods for opioid antagonist delivery |
| Assignee(s) | Purdue Pharma L.P. |