Synergistic Opioid Antagonist Delivery Systems

Publication ID: 24-11857547_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Opioid Antagonist Delivery Systems,” Published Technical Disclosure No. 24-11857547_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857547_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,547.

Summary of the Inventive Concept

The present inventive concept integrates opioid antagonist delivery with cutting-edge technologies like AI, IoT, blockchain, and novel materials to create more powerful and effective systems for opioid overdose rescue, prevention, and treatment.

Background and Problem Solved

The original patent addressed the need for improved opioid antagonist delivery systems. However, these systems were limited by their inability to adapt to individual patient needs, lack of real-time monitoring, and inadequate data security. The new inventive concept solves these problems by incorporating advanced technologies to enhance personalized treatment, real-time monitoring, and secure data management.

Detailed Description of the Inventive Concept

The inventive concept encompasses various synergistic combinations of opioid antagonist delivery systems with AI, IoT, blockchain, and novel materials. For instance, Claim 1 describes a wearable device with a sensor that detects opioid exposure, triggering automatic administration of an opioid antagonist via a blockchain-based platform. Claim 2 details a method for personalized opioid antagonist delivery using an IoT-enabled injector device that communicates with a cloud-based server. Claim 3 presents a composition that releases the antagonist in response to an electrical signal generated by a wearable device, triggered by a machine learning algorithm. These systems enable real-time monitoring, secure data storage, and personalized treatment, significantly improving opioid overdose rescue and prevention.

Novelty and Inventive Step

The new claims introduce the novel combination of opioid antagonist delivery with AI, IoT, blockchain, and novel materials, providing a significant inventive step over the original patent. The integration of these technologies enables real-time monitoring, secure data management, and personalized treatment, which are not present in the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT devices, or blockchain platforms. Variations could involve the integration of additional technologies, such as augmented reality or 5G networks, to further enhance the systems' capabilities.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical, healthcare, and technology industries. The systems could be marketed to hospitals, clinics, and emergency responders, as well as to individuals at risk of opioid overdose. The market size is substantial, with the global opioid antagonist market projected to reach $1.5 billion by 2025.

Original Patent Information

Patent NumberUS 11,857,547
TitleCompositions and methods for opioid antagonist delivery
Assignee(s)Purdue Pharma L.P.