Specialized Opioid Antagonist Formulations for Niche Environments

Publication ID: 24-11857547_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Opioid Antagonist Formulations for Niche Environments,” Published Technical Disclosure No. 24-11857547_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857547_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,547.

Summary of the Inventive Concept

Adapting opioid antagonist formulations for specific, narrow markets or unique operational environments, such as high-security needs, disaster relief, or extreme weather conditions.

Background and Problem Solved

The original patent provides compositions and methods for opioid antagonist delivery, but these formulations may not be suitable for specialized environments. The present inventive concept addresses the limitations of the original patent by developing tailored formulations for high-security, disaster relief, and extreme weather conditions.

Detailed Description of the Inventive Concept

The inventive concept comprises opioid antagonist formulations with specialized excipients, cryoprotectants, or other adaptations to ensure stability and potency in extreme temperatures, tropical environments, or low-light conditions. These formulations can be administered via rapid-dissolve tablets, wearable injector devices, or portable kits with auto-injector devices. The compositions are designed to provide effective opioid overdose rescue in unique operational environments.

Novelty and Inventive Step

The new claims introduce novel adaptations for opioid antagonist formulations, such as specialized excipients for extreme temperatures, cryoprotectants for freeze-dried compositions, and wearable injector devices for remote areas. These adaptations are non-obvious and provide a significant improvement over the original patent's formulations.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include opioid antagonist formulations adapted for use in high-altitude environments, underwater rescue scenarios, or for specific age groups or medical conditions. Variations could also include different routes of administration, such as nasal sprays or transdermal patches.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in industries such as pharmaceuticals, emergency medical services, disaster relief, and high-security operations. The targeted markets include government agencies, emergency responders, and organizations operating in extreme environments.

Original Patent Information

Patent NumberUS 11,857,547
TitleCompositions and methods for opioid antagonist delivery
Assignee(s)Purdue Pharma L.P.