Enhanced Dental and Medical Compositions with Improved Bioactivity and Mechanical Strength
Legal Citation
Summary of the Inventive Concept
This inventive concept relates to improved dental and medical compositions having a multiple source of metallic ions, which provide enhanced bioactivity, mechanical strength, and controlled release of ions for various medical and dental applications.
Background and Problem Solved
The original patent, 'Dental and medical compositions having a multiple source of metallic ions,' disclosed bioceramic compositions for endodontic applications. However, these compositions had limitations, such as slow dissolution rates, pH instability, and inadequate mechanical strength. The new inventive concept addresses these limitations by introducing improved multiparticulate crystalline multimetallic silicates, novel combinations of sorosilicates and setting agents, and adjustable particle sizes and surface areas.
Detailed Description of the Inventive Concept
The new inventive concept comprises dental and medical compositions featuring multiparticulate crystalline multimetallic silicates with improved dissolution rates and pH stability, enabling enhanced bioactivity in various applications. The compositions may include novel combinations of sorosilicates, such as Strontium-akermanite, Akermanite, Baghdadite, and Hardystonite, and setting agents like calcium sulfate, calcium acetate, calcium carbonate, calcium oxalate, and potassium sulfate. The multiparticulate crystalline multimetallic silicates can be formulated with adjustable particle sizes and surface areas to control the release of metallic ions. Additionally, the compositions may include optional further setting agents and liquid carriers to enhance their properties.
Novelty and Inventive Step
The new claims introduce several novel features, including the improved multiparticulate crystalline multimetallic silicates, the novel combinations of sorosilicates and setting agents, and the adjustable particle sizes and surface areas. These features provide enhanced bioactivity, mechanical strength, and controlled release of metallic ions, which are not obvious from the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include variations in the types and proportions of sorosilicates, setting agents, and liquid carriers used. Additionally, the multiparticulate crystalline multimetallic silicates could be formulated with different particle sizes and surface areas to suit specific medical or dental applications.
Potential Commercial Applications and Market
The enhanced dental and medical compositions of this inventive concept have significant commercial potential in various industries, including dentistry, orthopedics, and tissue engineering. They can be used in a range of applications, such as endodontic treatments, bone grafting, and implantable devices, offering improved performance, safety, and efficacy.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Dental and medical biomaterials, specifically bioceramic compositions for endodontic and tissue regeneration applications, requiring expertise in materials science, ceramic engineering, and medical device development
Person of Ordinary Skill (PHOSITA) Profile
A materials scientist or biomedical engineer with advanced degree, working knowledge of ceramic composition, ion release mechanisms, and dental/medical material formulation techniques, familiar with sorosilicate chemistry and bioactive material design
Obviousness Rationale
A PHOSITA would recognize that the PTD's variations represent predictable modifications of the source patent's bioceramic composition by systematically adjusting known sorosilicate components, setting agents, and particle characteristics to optimize bioactivity and mechanical performance. The disclosed combinations represent routine optimization of known material parameters within established compositional ranges. The technical variations demonstrate incremental improvements achievable through standard materials engineering approaches.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,558 |
|---|---|
| Title | Dental and medical compositions having a multiple source of metallic ions |
| Assignee(s) | ANGELUS INDUSTRIA DE PRODUTOS ODONTOLOGICOS S/A |