Enhanced Dental and Medical Compositions with Bioactive Metallic Ions

Publication ID: 24-11857558_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Dental and Medical Compositions with Bioactive Metallic Ions,” Published Technical Disclosure No. 24-11857558_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857558_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,558.

Summary of the Inventive Concept

This inventive concept improves upon existing dental and medical compositions by incorporating surface-treated multiparticulate crystalline multimetallic silicates, growth factors, antibacterial agents, and porous structures to enhance bioactivity, tissue regeneration, and antibacterial properties.

Background and Problem Solved

The original patent disclosed dental and medical compositions with a multiple source of metallic ions, but it had limitations in terms of bioactivity, tissue regeneration, and antibacterial properties. The new inventive concept addresses these limitations by introducing surface-treated multiparticulate crystalline multimetallic silicates, growth factors, antibacterial agents, and porous structures to create more effective and efficient compositions.

Detailed Description of the Inventive Concept

The enhanced dental and medical compositions comprise surface-treated multiparticulate crystalline multimetallic silicates, which provide a higher surface area for bioactivity. The silicates can be formulated with growth factors to promote cell proliferation and differentiation, and antibacterial agents to prevent bacterial growth. The compositions can be designed with porous structures to increase the surface area for bioactivity. The surface treatment of the silicates with bioactive molecules enhances their bioactivity, making them more effective in tissue regeneration and repair. The compositions can be used in various applications, including dental caries treatment, tissue regeneration, and bone repair.

Novelty and Inventive Step

The new claims introduce the concept of surface-treated multiparticulate crystalline multimetallic silicates, growth factors, antibacterial agents, and porous structures, which are not present in the original patent. These features provide a significant improvement over the existing compositions, making them more effective, efficient, and safe for use in dental and medical applications.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include different types of bioactive molecules for surface treatment, various growth factors for promoting cell proliferation and differentiation, and different antibacterial agents for preventing bacterial growth. The compositions could also be designed with different porous structures to optimize their bioactivity.

Potential Commercial Applications and Market

The enhanced dental and medical compositions have significant commercial potential in the dental and medical industries, particularly in the areas of tissue regeneration, bone repair, and dental caries treatment. The market for these compositions is expected to grow as the demand for more effective and efficient treatments increases.

Field of Art

Dental and medical biomaterials, specifically bioceramic compositions for tissue regeneration and dental treatments, requiring expertise in materials science, inorganic chemistry, and biomedical engineering

Person of Ordinary Skill (PHOSITA) Profile

A materials scientist or biomedical engineer with advanced degree, familiar with bioceramic composition design, surface modification techniques, and medical material development strategies

Obviousness Rationale

A PHOSITA would recognize that surface treatment of multiparticulate crystalline silicates, incorporation of growth factors, and design of porous structures represent predictable engineering variations to enhance bioactivity and functionality of the original bioceramic composition. These modifications align with standard biomedical material development strategies of improving surface interactions, cellular response, and material performance.

Obvious Combinations & Variations

Source Patent Element
Multiparticulate crystalline multimetallic silicates (e.g., Akermanite, Hardystonite)
PTD Variation
Surface-treating silicates with bioactive molecules to enhance bioactivity
Obviousness Reasoning
Surface modification is a known technique in biomaterials to improve cellular interactions, with predictable results of enhanced material performance and biocompatibility
Source Patent Element
Bioceramic composition for endodontic applications
PTD Variation
Incorporating growth factors to promote cell proliferation and differentiation
Obviousness Reasoning
Adding growth factors to biomaterials is a standard approach in tissue engineering to enhance regenerative capabilities, representing a predictable design optimization
Source Patent Element
Dental and medical composition with metallic ions
PTD Variation
Introducing antibacterial agents to prevent bacterial growth
Obviousness Reasoning
Integrating antibacterial components is a known strategy in medical materials to prevent infection, representing a logical extension of the original composition's therapeutic goals
Source Patent Element
Bioceramic powder composition
PTD Variation
Designing porous structures to increase surface area for bioactivity
Obviousness Reasoning
Creating porous architectures is a well-established method in materials science to enhance material interactions and performance, representing a predictable engineering solution
Source Patent Element
Endodontic application bioceramic composition
PTD Variation
Developing a comprehensive kit with instructions for tissue regeneration and repair
Obviousness Reasoning
Creating application-specific kits with detailed instructions is a standard practice in medical product development, representing a routine commercial adaptation
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857558, a Person Having Ordinary Skill In The Art would find the variations disclosed in this Published Technical Disclosure obvious, as the modifications represent predictable engineering solutions within the established framework of bioceramic composition design. The surface treatments, growth factor incorporation, antibacterial agents, and structural modifications constitute routine optimization strategies that would be apparent to a skilled practitioner in the field of dental and medical biomaterials.

Original Patent Information

Patent NumberUS 11,857,558
TitleDental and medical compositions having a multiple source of metallic ions
Assignee(s)ANGELUS INDUSTRIA DE PRODUTOS ODONTOLOGICOS S/A