Personalized Regenerative Dentistry with Customized Bioceramic Compositions

Publication ID: 24-11857558_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Regenerative Dentistry with Customized Bioceramic Compositions,” Published Technical Disclosure No. 24-11857558_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857558_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,558.

Summary of the Inventive Concept

A next-generation bioceramic composition technology that enables tailored release of metallic ions for specific tissue regeneration requirements, revolutionizing regenerative dentistry and oral tissue engineering.

Background and Problem Solved

The original patent disclosed a bioceramic composition with a multiple source of metallic ions for endodontic applications. However, this technology has limitations in terms of customization and adaptability to specific patient needs. The new inventive concept addresses these limitations by introducing a novel multiparticulate crystalline multimetallic silicate that can be engineered to release a customized ratio of metallic ions tailored to specific tissue regeneration requirements.

Detailed Description of the Inventive Concept

The new inventive concept involves a system for regenerative dentistry comprising a bioceramic composition with a novel multiparticulate crystalline multimetallic silicate. This silicate is designed to release a customized ratio of metallic ions tailored to specific tissue regeneration requirements. The bioceramic composition can be formulated to stimulate bone growth and differentiation at a specific rate, creating a microenvironment conducive to stem cell differentiation and tissue regeneration. The novel sorosilicate structure is engineered to release a sustained amount of calcium ions over an extended period, promoting long-term bone health. The inventive concept also encompasses methods for creating personalized dental implants, treating dental caries, and oral tissue engineering.

Novelty and Inventive Step

The new claims introduce a paradigm shift in bioceramic composition technology by enabling customization and adaptability to specific patient needs. The novel multiparticulate crystalline multimetallic silicate and its engineered release of metallic ions provide a non-obvious solution to the limitations of the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the type and ratio of metallic ions released, using different sorosilicate structures, or incorporating additional components to enhance tissue regeneration. Variations could also include adapting the bioceramic composition for use in other medical applications, such as orthopedic or cardiovascular tissue engineering.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the regenerative dentistry and oral tissue engineering markets. The ability to provide customized bioceramic compositions tailored to specific patient needs could revolutionize the treatment of dental caries and other oral health issues, with potential applications in personalized medicine and tissue engineering.

Field of Art

Biomaterials and Dental Regenerative Technologies, with expertise in bioceramic compositions, metallic ion release systems, and tissue engineering techniques

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in materials science, bioengineering, or dental materials, possessing knowledge of sorosilicate structures, ion release mechanisms, and regenerative medicine principles

Obviousness Rationale

A skilled practitioner would recognize that the PTD represents a predictable extension of the source patent's bioceramic composition technology by introducing customized ion release and targeted tissue regeneration strategies. The fundamental sorosilicate structure remains consistent with the original patent, while the novel approach focuses on tailoring metallic ion ratios for specific therapeutic outcomes. These modifications represent routine optimization within the established technological framework of the source patent.

Obvious Combinations & Variations

Source Patent Element
Sorosilicate compositions with specific metallic ion structures (e.g., Strontium-akermanite, Akermanite)
PTD Variation
Customized metallic ion release ratios for targeted tissue regeneration
Obviousness Reasoning
Predictable variation using known sorosilicate engineering principles to modify ion release characteristics for specific medical applications
Source Patent Element
Bioceramic composition for endodontic applications
PTD Variation
Personalized dental implant systems with engineered stem cell microenvironments
Obviousness Reasoning
Logical extension of existing bioceramic technology to create more specialized tissue engineering solutions using known material modification techniques
Source Patent Element
Calcium sulfate as a setting agent in bioceramic compositions
PTD Variation
Enhanced calcium ion release mechanisms for promoting long-term bone health
Obviousness Reasoning
Routine optimization of existing ion release strategies using well-understood material science principles
Source Patent Element
Multiparticulate crystalline multimetallic silicate structures
PTD Variation
Tailored sorosilicate designs for specific tissue regeneration requirements
Obviousness Reasoning
Predictable design variation using known material engineering techniques to adapt existing compositional frameworks
Source Patent Element
Dental and medical composition with metallic ion components
PTD Variation
Bacterial growth inhibition and tooth remineralization through controlled ion release
Obviousness Reasoning
Obvious application of known ion release principles to address specific dental treatment challenges
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857558, the present publication demonstrates that the claimed variations in bioceramic composition technology represent obvious extensions of existing sorosilicate material design principles. A person having ordinary skill in the art would readily recognize that the disclosed personalized regenerative dentistry techniques constitute predictable variations of the prior art, employing routine optimization strategies within the established technological framework of metallic ion-based biomaterials.

Original Patent Information

Patent NumberUS 11,857,558
TitleDental and medical compositions having a multiple source of metallic ions
Assignee(s)ANGELUS INDUSTRIA DE PRODUTOS ODONTOLOGICOS S/A