Specialized Pharmaceutical Compositions for High-Risk Environments
Legal Citation
Summary of the Inventive Concept
This inventive concept adapts pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections in high-security needs, disaster relief, extreme weather conditions, remote areas, and high-altitude environments.
Background and Problem Solved
The original patent disclosed nucleotide and nucleoside therapeutic compositions for treating viral infections. However, these compositions may not be suitable for high-risk environments, such as high-security facilities, disaster-stricken areas, extreme weather conditions, remote areas, and high-altitude environments, where specialized delivery devices, resistant excipients, and adapted formulations are required.
Detailed Description of the Inventive Concept
The new inventive concept comprises pharmaceutical compositions of Formula Im:, or a pharmaceutically acceptable salt or tautomer thereof, adapted for high-security needs, disaster relief, extreme weather conditions, remote areas, and high-altitude environments. The compositions may include security-enhanced delivery devices, excipients resistant to degradation under extreme weather conditions, and portable, solar-powered refrigeration units. The adapted formulations and delivery systems enable effective treatment of viral infections in these high-risk environments.
Novelty and Inventive Step
The new claims introduce novel adaptations of the original pharmaceutical compositions for treating viral infections, including specialized delivery devices, excipients, and formulations tailored to high-security needs, disaster relief, extreme weather conditions, remote areas, and high-altitude environments. These adaptations provide a non-obvious solution to the limitations of the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include varying the type of security-enhanced delivery device, using different excipients resistant to degradation under extreme weather conditions, or incorporating additional features into the portable, solar-powered refrigeration unit. Variations may also include adapting the pharmaceutical compositions for treating viral infections in other high-risk environments, such as confined spaces or areas with limited medical resources.
Potential Commercial Applications and Market
The specialized pharmaceutical compositions for high-risk environments have significant commercial potential in industries such as biotechnology, pharmaceuticals, and disaster relief. The target market includes government agencies, non-profit organizations, and private companies operating in high-security facilities, disaster-stricken areas, extreme weather conditions, remote areas, and high-altitude environments.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical Composition Design, Specifically Nucleotide and Nucleoside Therapeutic Formulations with a Focus on Viral Infection Treatment and Specialized Delivery Systems
Person of Ordinary Skill (PHOSITA) Profile
A pharmaceutical scientist or chemical engineer with advanced degree, expertise in drug formulation, delivery system design, and experience with nucleoside/nucleotide therapeutic compositions, familiar with adapting pharmaceutical products for challenging environmental conditions
Obviousness Rationale
A PHOSITA would recognize that adapting pharmaceutical compositions for extreme environments represents a standard engineering challenge involving predictable modifications to existing formulations. The source patent provides a foundational nucleotide composition that can be readily modified through known pharmaceutical techniques to address specific environmental challenges. The variations disclosed in the PTD represent logical extensions of the original patent's core technological framework, utilizing standard pharmaceutical engineering approaches to enhance drug delivery and stability.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,560 |
|---|---|
| Title | Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections |
| Assignee(s) | Emory University |