RNA-based Immunization Delivery Systems for Environmental Remediation

Publication ID: 24-11857562_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “RNA-based Immunization Delivery Systems for Environmental Remediation,” Published Technical Disclosure No. 24-11857562_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857562_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,562.

Summary of the Inventive Concept

This inventive concept leverages the core technology of RNA-based immunization delivery systems to tackle environmental pollutants and pests in various industries, including wastewater treatment, bioremediation, agriculture, and industrial emissions monitoring.

Background and Problem Solved

The original patent addressed the delivery of RNA for immunization in the field of non-viral delivery. However, the patent's scope was limited to immunizing animals. The new inventive concept solves the problem of applying RNA-based immunization delivery systems to entirely new fields, addressing the pressing issue of environmental pollution and its devastating consequences.

Detailed Description of the Inventive Concept

The RNA-based immunization delivery system is adapted to trigger an immune response against pollutants in wastewater, contaminated soil, agricultural pests, and industrial emissions. The system comprises RNA molecules designed to stimulate an immune response, which are then delivered using liposomes or other non-viral vectors. The RNA molecules can be modified to enhance stability, efficacy, and specificity. The system can be integrated into existing infrastructure, such as wastewater treatment plants or agricultural systems, to provide a novel solution for environmental remediation.

Novelty and Inventive Step

The new claims introduce a novel application of RNA-based immunization delivery systems to environmental remediation, which is non-obvious and unforeseen from the original patent. The inventive step lies in the adaptation of the core technology to address a completely different problem domain, requiring significant modifications and innovations to the original system.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different types of RNA molecules, such as siRNA or miRNA, or exploring various delivery methods, such as nanoparticles or viral vectors. Variations could also involve targeting different types of pollutants or pests, or integrating the system with existing technologies, such as sensors or monitoring systems.

Potential Commercial Applications and Market

The RNA-based immunization delivery system for environmental remediation has vast commercial potential, with applications in wastewater treatment, bioremediation, agriculture, and industrial emissions monitoring. The market size is significant, with the global environmental remediation market projected to reach billions of dollars in the coming years. The inventive concept has the potential to disrupt traditional methods of environmental remediation and provide a novel, effective, and sustainable solution.

Original Patent Information

Patent NumberUS 11,857,562
TitleDelivery of RNA to trigger multiple immune pathways
Assignee(s)GlaxoSmith Kline Biologicals S.A.