Pathogenic Age-Associated B Cells for Environmental and Agricultural Applications

Publication ID: 24-11857563_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Pathogenic Age-Associated B Cells for Environmental and Agricultural Applications,” Published Technical Disclosure No. 24-11857563_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857563_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,563.

Summary of the Inventive Concept

This inventive concept leverages the core technology of targeting pathogenic age-associated B cells to develop novel applications in environmental monitoring, agricultural optimization, and personalized skincare, expanding the original patent's scope beyond autoimmune disease treatment.

Background and Problem Solved

The original patent focused on treating autoimmune diseases by targeting pathogenic age-associated B cells. However, the limitations of this approach lie in its narrow focus on human health. This new inventive concept addresses the need for innovative solutions in environmental monitoring, agricultural optimization, and personalized skincare, where the unique properties of pathogenic age-associated B cells can be harnessed to create impactful technologies.

Detailed Description of the Inventive Concept

The new inventive concept comprises a range of applications that utilize pathogenic age-associated B cells as biosensors, biostimulants, or biomarkers. In environmental monitoring, these biosensors detect and respond to specific pollutants, enabling real-time monitoring of environmental pollution. In agricultural optimization, the biostimulants enhance plant growth and resistance to disease, increasing crop yields. In personalized skincare, the biomarkers identify specific skin types and conditions, enabling the creation of customized skincare products. These applications are made possible by the unique properties of pathogenic age-associated B cells, which can be engineered to respond to specific stimuli and provide accurate, real-time data.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the application of pathogenic age-associated B cells, moving beyond autoimmune disease treatment to address pressing issues in environmental monitoring, agricultural optimization, and personalized skincare. The inventive step lies in recognizing the potential of these cells to serve as biosensors, biostimulants, or biomarkers, and developing novel systems and methods that harness their unique properties.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using pathogenic age-associated B cells to detect and respond to other environmental pollutants, or to optimize crop yields in specific agricultural contexts. Variations could also involve integrating these cells with other technologies, such as machine learning algorithms or IoT devices, to create more sophisticated monitoring and optimization systems.

Potential Commercial Applications and Market

The potential commercial applications of this inventive concept are vast, with opportunities in environmental monitoring, agricultural optimization, and personalized skincare. The target industries include environmental consulting, agricultural technology, and cosmetics, with potential partnerships with companies, research institutions, and government agencies.

Original Patent Information

Patent NumberUS 11,857,563
TitleInhibition of expansion and function of pathogenic age-associated B cells and use for the prevention and treatment of autoimmune disease
Assignee(s)NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED, MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY