Synergistic Combinations for Autoimmune Disease Prevention and Treatment

The inventive concept integrates the original patented method for targeting pathogenic age-associated B cells with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for diagnosing, preventing, and treating autoimmune diseases.

The original patent provides a method for treating autoimmune diseases by targeting pathogenic age-associated B cells. However, the patent has limitations in terms of diagnosis, prevention, and treatment. The new inventive concept addresses these limitations by combining the original method with advanced technologies to create a more comprehensive and effective system.

The inventive concept comprises five synergistic combinations: 1) a machine learning model and blockchain-based secure data storage system for diagnosing autoimmune diseases, 2) a method for preventing autoimmune disease using IoT-enabled wearable devices, 3) a nanoparticle-based delivery system and graphene-based sensor for treating lymphoproliferative disorders, 4) a deep learning model and cloud-based computing platform for predicting autoimmune disease risk, and 5) a natural language processing-based AI system and CRISPR-Cas9-based gene editing system for identifying novel therapeutic targets.

The new claims introduce novel combinations of the original patented method with advanced technologies, providing a more comprehensive and effective system for diagnosing, preventing, and treating autoimmune diseases. The inventive step lies in the unexpected integration of these distinct technologies to create a synergistic system that overcomes the limitations of the original patent.

Alternative embodiments of the inventive concept could include using different machine learning models, blockchain platforms, or IoT devices. Variations could include applying the system to different autoimmune diseases or using different nanoparticle-based delivery systems.

The inventive concept has significant commercial potential in the healthcare industry, particularly in the fields of autoimmune disease diagnosis, prevention, and treatment. The market for autoimmune disease treatments is projected to grow significantly in the coming years, and the inventive concept is well-positioned to capitalize on this trend.