Specialized Hypertonic Compositions for Niche Environments
Legal Citation
Summary of the Inventive Concept
This inventive concept adapts hypertonic pharmaceutical compositions containing anti-platinum chemoprotectant agents for specific, narrow markets or unique operational environments, such as high-altitude, disaster relief, high-security, extreme weather conditions, and remote, off-grid settings.
Background and Problem Solved
The original patent provided hypertonic pharmaceutical compositions containing anti-platinum chemoprotectant agents for general use. However, these compositions may not be suitable for specific environments where additional challenges, such as extreme temperatures, high altitudes, or limited resources, are present. This inventive concept addresses these limitations by adapting the compositions for these niche environments.
Detailed Description of the Inventive Concept
The new claims describe hypertonic pharmaceutical compositions containing anti-platinum chemoprotectant agents, tailored for specific environments. For high-altitude environments, the compositions have a calculated osmolarity of at least 1,500 mOsm/L. For disaster relief settings, the compositions are packaged in portable, waterproof containers. In high-security environments, the compositions are formulated to withstand temperatures above 100°F. For extreme weather conditions, the compositions are packaged in weather-resistant containers. In remote, off-grid settings, the compositions are formulated to be stable at room temperature for at least 6 months.
Novelty and Inventive Step
The new claims introduce novel adaptations of the original compositions, making them suitable for specific environments. The inventive step lies in the tailored design of the compositions to address the unique challenges of each environment, which is not obvious from the original patent.
Alternative Embodiments and Variations
Other embodiments of this inventive concept could include adaptations for space exploration, underwater operations, or extreme humidity environments. Additionally, the compositions could be formulated for use in veterinary medicine or for protecting hearing in individuals with pre-existing hearing loss.
Potential Commercial Applications and Market
This inventive concept has significant commercial potential in the pharmaceutical industry, particularly in the areas of oncology and otolaryngology. The adapted compositions could be marketed to healthcare providers, emergency responders, and military organizations operating in challenging environments.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical formulations, specifically hypertonic compositions for chemoprotection and hearing loss prevention, requiring expertise in pharmaceutical chemistry, drug delivery systems, and medical applications
Person of Ordinary Skill (PHOSITA) Profile
A pharmaceutical chemist or formulation scientist with advanced degree, experience in drug delivery, knowledge of osmolarity manipulation, stability testing, and environmental adaptation of pharmaceutical compositions
Obviousness Rationale
A person having ordinary skill would recognize that the source patent's hypertonic pharmaceutical compositions could be readily adapted for specific environmental conditions by modifying osmolarity, packaging, and stability parameters. The core technical principles of anti-platinum chemoprotection remain consistent across the disclosed variations. The PTD represents predictable extensions of known pharmaceutical formulation techniques applied to a well-understood therapeutic approach.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,567 |
|---|---|
| Title | Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent |
| Assignee(s) | Decibel Therapeutics, Inc. |