Specialized Hypertonic Compositions for Niche Environments

Publication ID: 24-11857567_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Hypertonic Compositions for Niche Environments,” Published Technical Disclosure No. 24-11857567_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857567_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,567.

Summary of the Inventive Concept

This inventive concept adapts hypertonic pharmaceutical compositions containing anti-platinum chemoprotectant agents for specific, narrow markets or unique operational environments, such as high-altitude, disaster relief, high-security, extreme weather conditions, and remote, off-grid settings.

Background and Problem Solved

The original patent provided hypertonic pharmaceutical compositions containing anti-platinum chemoprotectant agents for general use. However, these compositions may not be suitable for specific environments where additional challenges, such as extreme temperatures, high altitudes, or limited resources, are present. This inventive concept addresses these limitations by adapting the compositions for these niche environments.

Detailed Description of the Inventive Concept

The new claims describe hypertonic pharmaceutical compositions containing anti-platinum chemoprotectant agents, tailored for specific environments. For high-altitude environments, the compositions have a calculated osmolarity of at least 1,500 mOsm/L. For disaster relief settings, the compositions are packaged in portable, waterproof containers. In high-security environments, the compositions are formulated to withstand temperatures above 100°F. For extreme weather conditions, the compositions are packaged in weather-resistant containers. In remote, off-grid settings, the compositions are formulated to be stable at room temperature for at least 6 months.

Novelty and Inventive Step

The new claims introduce novel adaptations of the original compositions, making them suitable for specific environments. The inventive step lies in the tailored design of the compositions to address the unique challenges of each environment, which is not obvious from the original patent.

Alternative Embodiments and Variations

Other embodiments of this inventive concept could include adaptations for space exploration, underwater operations, or extreme humidity environments. Additionally, the compositions could be formulated for use in veterinary medicine or for protecting hearing in individuals with pre-existing hearing loss.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential in the pharmaceutical industry, particularly in the areas of oncology and otolaryngology. The adapted compositions could be marketed to healthcare providers, emergency responders, and military organizations operating in challenging environments.

Original Patent Information

Patent NumberUS 11,857,567
TitleHypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent
Assignee(s)Decibel Therapeutics, Inc.