Personalized Alzheimer's Disease Prevention and Monitoring System

Publication ID: 24-11857568_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Alzheimer's Disease Prevention and Monitoring System,” Published Technical Disclosure No. 24-11857568_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857568_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,568.

Summary of the Inventive Concept

A next-generation system for personalized Alzheimer's disease prevention and monitoring, leveraging genomic analysis, machine learning, and tailored vaccine compositions to prevent disease onset and track progression in real-time.

Background and Problem Solved

The original patent addressed the treatment and prevention of Alzheimer's disease, but its limitations included a focus on pharmaceutical formulations and lack of personalization. The new inventive concept addresses these limitations by introducing a system that integrates genomic analysis, machine learning, and tailored vaccine compositions to provide personalized prevention and monitoring.

Detailed Description of the Inventive Concept

The system comprises a genomic analysis module that identifies genetic markers associated with β-amyloid deposition, a treatment module that administers a tailored vaccine composition based on an individual's genetic profile, and a wearable device for monitoring Alzheimer's disease progression. The genomic analysis module utilizes machine learning algorithms to predict the likelihood of Alzheimer's disease onset. The vaccine composition is generated by selecting a plurality of β-amyloid peptides and combining them with an adjuvant to enhance immunogenicity, inducing a targeted immune response against β-amyloid deposition.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift in Alzheimer's disease prevention and monitoring by integrating genomic analysis, machine learning, and tailored vaccine compositions. The inventive step lies in the combination of these components to provide personalized prevention and monitoring, which is not addressed by the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include using different types of machine learning algorithms, incorporating additional biomarkers, or integrating with electronic health records. Variations may include developing a mobile application for patient engagement, creating a cloud-based platform for data analysis, or incorporating artificial intelligence for predictive analytics.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the healthcare industry, particularly in the areas of personalized medicine, precision health, and Alzheimer's disease prevention. The target market includes pharmaceutical companies, biotech firms, and healthcare providers seeking innovative solutions for Alzheimer's disease prevention and monitoring.

Original Patent Information

Patent NumberUS 11,857,568
TitleTreatment and prevention of Alzheimer's disease (AD)
Assignee(s)Advantage Therapeutics, Inc.