Enhanced Ozonized Olive Oil Compositions for Topical Treatment of Vulvovaginitis

Publication ID: 24-11857570_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Ozonized Olive Oil Compositions for Topical Treatment of Vulvovaginitis,” Published Technical Disclosure No. 24-11857570_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857570_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,570.

Summary of the Inventive Concept

The present inventive concept relates to an improved ozonized olive oil composition for the topical treatment of vulvovaginitis, featuring a broader range of natural ingredients, pH buffering, and enhanced moisturizing properties.

Background and Problem Solved

Vulvovaginitis is a common and recurring problem affecting women worldwide. The original patent disclosed an ozonized olive oil composition with limited natural ingredients, which may not provide optimal treatment outcomes. The present inventive concept addresses the limitations of the original patent by introducing a more comprehensive range of natural ingredients, pH buffering, and moisturizing properties to create a more effective and user-friendly composition.

Detailed Description of the Inventive Concept

The enhanced ozonized olive oil composition comprises an ozonized olive oil having a peroxide value of 50-350 mEq O2/Kg and at least one liquid vegetable extract selected from among Allium spp., Aloe spp., Calendula officinalis, Cinnamomum spp., Curcuma spp., Lavender spp., Melaleuca spp., Plantago, Salvia officinalis, Salvia miltiorrhiza, Thymus spp., Zingiber spp., and mixtures thereof. The composition may further include a pH buffering agent to maintain a pH range of 4.5-5.5, and a moisturizing agent to enhance skin hydration. The inventive concept also encompasses methods for preparing and using the composition, as well as a kit for treating vulvovaginitis.

Novelty and Inventive Step

The new claims introduce a broader range of natural ingredients, pH buffering, and moisturizing properties, which are not anticipated by the original patent. The combination of these features provides a more effective and user-friendly composition for the topical treatment of vulvovaginitis.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include varying the concentration of the ozonized olive oil, using different types of vegetable extracts, or incorporating additional ingredients to enhance the composition's efficacy. Variations of the method for preparing the composition may include using different mixing protocols or adding preservatives to extend the shelf life.

Potential Commercial Applications and Market

The enhanced ozonized olive oil composition has significant commercial potential in the gynecology and dermatology markets, offering a natural, effective, and user-friendly solution for the topical treatment of vulvovaginitis. The composition may be marketed as an over-the-counter or prescription product, and its moisturizing properties may also appeal to consumers seeking natural skincare products.

Field of Art

Pharmaceutical and cosmetic compositions for topical treatment of gynecological infections, with expertise in natural extract formulations, ozonization techniques, and dermatological delivery systems

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced training in pharmaceutical chemistry, botanical extract preparation, and topical drug delivery, possessing knowledge of natural antimicrobial compounds and formulation techniques

Obviousness Rationale

A person of ordinary skill would recognize that expanding the range of natural vegetable extracts and adding pH buffering and moisturizing agents represents a predictable variation of the source patent's core composition. The technical modifications are consistent with standard pharmaceutical development practices for improving topical treatment formulations. The additional ingredients and methods would be considered routine optimization within the established framework of the original ozonized olive oil composition.

Obvious Combinations & Variations

Source Patent Element
Ozonized olive oil with Calendula officinalis and Melaleuca spp. extracts
PTD Variation
Expanding extract selection to include additional botanical species like Allium spp., Aloe spp., Lavender spp., and others
Obviousness Reasoning
Known botanical extracts with established antimicrobial properties represent a finite set of predictable substitutions for a skilled formulator
Source Patent Element
Topical ointment/cream formulation for vulvovaginitis treatment
PTD Variation
Adding pH buffering agent to maintain 4.5-5.5 pH range
Obviousness Reasoning
Adjusting formulation pH is a standard technique for optimizing topical medication stability and efficacy
Source Patent Element
Ozonized olive oil composition with 50-350 mEq O2/Kg peroxide value
PTD Variation
Incorporating moisturizing agents to enhance skin hydration
Obviousness Reasoning
Complementary ingredient addition to improve user experience and treatment comfort is an obvious design optimization
Source Patent Element
Liquid vegetable extract concentration of 0.5-10% by weight
PTD Variation
Introducing broader range of extract combinations and proportions
Obviousness Reasoning
Routine experimentation with ingredient ratios represents standard pharmaceutical development practice
Source Patent Element
Topical treatment method for vulvovaginitis
PTD Variation
Adding preservative to extend composition shelf life
Obviousness Reasoning
Preservation techniques are well-known standard practices in pharmaceutical and cosmetic formulation
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857570, the present publication demonstrates that the claimed variations in botanical extract selection, formulation pH, moisturizing properties, and preservation techniques would have been obvious to a person having ordinary skill in pharmaceutical composition development at the time of invention. The disclosed modifications represent predictable extensions of the prior art, utilizing known techniques and ingredients within the established compositional framework.

Original Patent Information

Patent NumberUS 11,857,570
TitleNatural composition for use in gynecology
Assignee(s)ORGANICARE LLC