Advanced Ozonized Olive Oil Formulations for Enhanced Vulvovaginitis Treatment

Publication ID: 24-11857570_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Advanced Ozonized Olive Oil Formulations for Enhanced Vulvovaginitis Treatment,” Published Technical Disclosure No. 24-11857570_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857570_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,570.

Summary of the Inventive Concept

The present inventive concept envisions next-generation ozonized olive oil formulations that overcome the limitations of traditional treatments for vulvovaginitis, providing enhanced efficacy, convenience, and patient comfort.

Background and Problem Solved

Vulvovaginitis remains a prevalent and recurring problem for women, with existing treatments often being inadequate or inconvenient. The original patent disclosed ozonized olive oil compositions with natural extracts, but these may not provide sustained relief or address the root causes of the infection. The new inventive concept addresses these limitations by introducing novel formulations and delivery systems that enhance the antimicrobial activity, bioavailability, and user experience of ozonized olive oil treatments.

Detailed Description of the Inventive Concept

The new inventive concept encompasses four key aspects: 1) encapsulation of ozonized olive oil in biodegradable nanoparticles for controlled release and targeted delivery; 2) pH-level maintenance in the vulvovaginal area to create an environment inhospitable to microbial growth; 3) synergistic blending of antimicrobial peptides and prebiotic fibers to enhance the antimicrobial activity of ozonized olive oil; and 4) development of devices such as vaginal rings or pessaries for sustained release and convenient administration. These advancements enable more effective, convenient, and patient-centric treatments for vulvovaginitis.

Novelty and Inventive Step

The new claims introduce significant innovations over the original patent, including the use of nanoparticles, pH-level control, and synergistic blending of antimicrobial peptides and prebiotic fibers. These advancements provide a paradigm shift in the treatment of vulvovaginitis, offering improved efficacy, convenience, and patient comfort.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different nanoparticle materials, varying the pH-level range, or incorporating additional natural extracts or antimicrobial agents. Variations may also involve different device designs or administration routes, such as creams, gels, or foams.

Potential Commercial Applications and Market

The advanced ozonized olive oil formulations and delivery systems have significant commercial potential in the women's health and gynecology markets, offering a novel solution for the treatment and prevention of vulvovaginitis. The target industries include pharmaceutical companies, medical device manufacturers, and healthcare providers.

Original Patent Information

Patent NumberUS 11,857,570
TitleNatural composition for use in gynecology
Assignee(s)ORGANICARE LLC