Personalized Hepatic Disease Treatment and Management System
Legal Citation
Summary of the Inventive Concept
A comprehensive system integrating genomics, machine learning, and wearable technologies to provide tailored treatments and real-time monitoring for hepatic diseases, revolutionizing patient care and outcomes.
Background and Problem Solved
The original patent disclosed compositions and methods for treating hepatic diseases, but it lacked personalization and real-time monitoring capabilities. The new inventive concept addresses these limitations by incorporating genomics, machine learning, and wearable technologies to provide a holistic approach to hepatic disease management.
Detailed Description of the Inventive Concept
The system comprises a genomics-based diagnostic module that identifies a patient's specific genetic profile, a tailored therapeutic formulation adapted to the patient's genetic profile, and a wearable device for non-invasive monitoring of liver health. The system also includes a machine learning-based platform for optimizing therapeutic regimens and a 3D-bioprinted liver tissue model for testing and validating novel therapeutic formulations. The system's components interact to provide real-time feedback and recommendations for personalized treatment and lifestyle modifications.
Novelty and Inventive Step
The new claims introduce a paradigm shift in hepatic disease treatment by integrating genomics, machine learning, and wearable technologies to provide personalized and real-time monitoring capabilities. The inventive concept's novelty lies in its ability to adapt to individual patients' genetic profiles and provide tailored treatments, which is a significant departure from the original patent's composition-based approach.
Alternative Embodiments and Variations
Alternative embodiments may include using different types of biomarkers or sensors for monitoring liver health, or incorporating additional data sources, such as electronic health records or medical imaging data, to enhance the system's predictive capabilities. Variations may also include adapting the system for use in other disease areas, such as cancer or cardiovascular disease.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the healthcare industry, particularly in the areas of personalized medicine, precision health, and digital health. The system's ability to provide real-time monitoring and tailored treatments could lead to improved patient outcomes, reduced healthcare costs, and increased market share for pharmaceutical and biotechnology companies.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biotechnology and personalized medicine, with expertise in hepatic disease treatment, genomics, therapeutic formulation development, and medical device integration
Person of Ordinary Skill (PHOSITA) Profile
A professional with advanced degrees in biotechnology, molecular biology, or biomedical engineering, possessing knowledge of immunological treatments, genomic analysis, machine learning applications in healthcare, and medical device design
Obviousness Rationale
A PHOSITA would recognize that the personalized medicine system represents a predictable extension of the source patent's immunological formulation approach by integrating genomic analysis, machine learning, and targeted therapeutic delivery. The core innovation of adapting the Gram-positive bacterial lysate formulation to a patient-specific treatment paradigm would be considered an obvious progression in precision medicine. The systematic approach of tailoring treatment based on genetic markers and developing advanced monitoring technologies follows established trends in personalized healthcare research.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,577 |
|---|---|
| Title | Compositions and methods for the treatment of hepatic diseases and disorders |
| Assignee(s) | Labyrinth Holdings, LLC |