Personalized Skin Treatment System with AI-Driven Bacterial Extracts

Publication ID: 24-11857578_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Skin Treatment System with AI-Driven Bacterial Extracts,” Published Technical Disclosure No. 24-11857578_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857578_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,578.

Summary of the Inventive Concept

A next-generation skin treatment system that leverages machine learning algorithms, skin microbiome analysis, and customized bacterial extracts to provide personalized solutions for sensitive skin and cutaneous neurogenic inflammation.

Background and Problem Solved

The original patent disclosed a novel bacterial extract for treating sensitive skin, but it had limitations in terms of individualized treatment and adaptability to varying skin profiles. The new inventive concept addresses these limitations by integrating AI-driven prediction models, skin microbiome analysis, and targeted delivery systems to create a more effective and personalized approach to skin treatment.

Detailed Description of the Inventive Concept

The system comprises a bacterial extract of a non-pathogenic Gram-negative bacterium belonging to the class Betaproteobacteria, subfamily Neisseriaceae, which is tailored to an individual's specific skin profile using machine learning algorithms and skin microbiome analysis. The system also includes a nanocarrier for targeted delivery to sensitive skin areas, which releases the bacterial extract in response to changes in skin pH. Additionally, a wearable device with a sensor for detecting changes in skin pH and a microcontroller for releasing the customized bacterial extract can be used to monitor skin health and provide real-time treatment.

Novelty and Inventive Step

The new claims introduce the concept of personalized skin treatment using AI-driven prediction models, skin microbiome analysis, and targeted delivery systems, which are not present in the original patent. The inventive step lies in the integration of these components to create a more effective and adaptable skin treatment system.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different machine learning algorithms, varying types of nanocarriers, or alternative sensors for detecting changes in skin pH. Additionally, the system could be adapted for use in treating other skin conditions, such as acne or rosacea.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the cosmetics and dermatology industries, particularly in the growing market for personalized skin care and treatment. The system could be marketed as a premium product for individuals seeking tailored solutions for sensitive skin and cutaneous neurogenic inflammation.

Field of Art

Dermatological biotechnology, focusing on bacterial extracts for skin treatment, with expertise in microbiology, microbiome analysis, and personalized medical technologies

Person of Ordinary Skill (PHOSITA) Profile

A researcher or biotechnologist with advanced degrees in microbiology or bioengineering, familiar with bacterial genomics, skin microbiome research, and emerging personalized medicine technologies

Obviousness Rationale

A PHOSITA would recognize that the personalized skin treatment system represents a predictable technological extension of the source patent's bacterial extract technology. The integration of machine learning, microbiome analysis, and targeted delivery systems are logical next-generation applications of the original bacterial extract invention. These variations represent standard technological progression using known techniques in biotechnology and personalized medicine.

Obvious Combinations & Variations

Source Patent Element
Bacterial extract from non-pathogenic Gram-negative bacterium with specific 16S rRNA sequence
PTD Variation
Machine learning algorithm for predicting skin sensitivity and tailoring bacterial extract selection
Obviousness Reasoning
Applying computational methods to biological sample selection is a known technique in biotechnology, representing a predictable application of existing knowledge
Source Patent Element
Method for treating cutaneous neurogenic inflammation
PTD Variation
Nanocarrier-based targeted delivery system responsive to skin pH changes
Obviousness Reasoning
Targeted drug delivery using responsive nanocarriers is a well-established technique in pharmaceutical engineering, representing an obvious optimization of treatment methods
Source Patent Element
Bacterial extract with specific genetic characteristics
PTD Variation
Database-driven selection of bacteria with known skin benefits for personalized microbiome management
Obviousness Reasoning
Creating curated biological databases for precision medicine is a standard approach in contemporary biotechnology research
Source Patent Element
Bacterial extract for skin treatment
PTD Variation
Wearable device with integrated pH sensor and microcontroller for real-time bacterial extract delivery
Obviousness Reasoning
Combining sensing technologies with targeted therapeutic delivery represents a predictable technological convergence in personalized medical devices
Source Patent Element
Non-pathogenic bacterial extract for skin treatment
PTD Variation
Expanding treatment applications to multiple skin conditions using microbiome analysis
Obviousness Reasoning
Generalizing medical treatments across related conditions is a standard scientific approach with predictable research progression
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857578, a person of ordinary skill in the art would find the variations disclosed in this publication to represent obvious technological extensions. The combination of machine learning, microbiome analysis, and targeted delivery systems constitutes a predictable advancement in bacterial extract technologies for dermatological applications, thereby rendering potential derivative claims obvious under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,578
TitleExtract and dermatological composition comprising same, for treating sensitive skin
Assignee(s)PIERRE FABRE DERMO-COSMETIQUE