Personalized FGF21 Secretion Optimization System

Publication ID: 24-11857579_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized FGF21 Secretion Optimization System,” Published Technical Disclosure No. 24-11857579_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857579_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,579.

Summary of the Inventive Concept

A next-generation system for optimizing FGF21 secretion through personalized microorganism selection, genetic analysis, and real-time monitoring, enabling targeted FGF21 delivery and enhanced overall health.

Background and Problem Solved

The original patent disclosed a composition for promoting FGF21 secretion using Bifidobacterium breve M-16V. However, this approach has limitations, as it is a one-size-fits-all solution that does not account for individual genetic profiles or gut microbiome compositions. The new inventive concept addresses this limitation by introducing a personalized system that tailors FGF21 secretion optimization to each individual's unique characteristics.

Detailed Description of the Inventive Concept

The system comprises a microorganism repository, a genetic analyzer, and a recommendation engine. The microorganism repository stores multiple strains of Bifidobacterium, each with distinct FGF21 secretion-promoting capabilities. The genetic analyzer assesses the subject's genetic profile, and the recommendation engine selects the optimal Bifidobacterium strain based on this analysis. The system can also integrate real-time FGF21 monitoring using wearable devices, enabling continuous optimization and refinement of the FGF21 secretion-promoting strategy. Additionally, the system can be used to design novel Bifidobacterium strains with enhanced FGF21 secretion-promoting capabilities through computer-aided genetic design and simulation.

Novelty and Inventive Step

The new claims introduce a paradigm shift in FGF21 secretion optimization by incorporating personalized genetic analysis, machine learning algorithms, and real-time monitoring. This approach is distinct from the original patent's composition-based approach and provides a more targeted and effective solution for promoting FGF21 secretion.

Alternative Embodiments and Variations

Alternative embodiments of the system could include the use of different microorganisms, such as Lactobacillus or Streptococcus, or the integration of additional data sources, such as gut microbiome composition or environmental factors. The system could also be adapted for use in various industries, including pharmaceuticals, nutrition, and wellness.

Potential Commercial Applications and Market

The personalized FGF21 secretion optimization system has significant commercial potential in the healthcare and wellness industries, particularly in the areas of metabolic disorders, weight management, and anti-aging. The system could be marketed as a premium service or product, offering individuals a tailored solution for optimizing their FGF21 secretion and overall health.

Original Patent Information

Patent NumberUS 11,857,579
TitleComposition for promoting the secretion of FGF21
Assignee(s)Morinaga Milk Industry Co., Ltd.