Adapted Lactobacillus Composition for Specialized Vaginal Health Applications

Publication ID: 24-11857580_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Adapted Lactobacillus Composition for Specialized Vaginal Health Applications,” Published Technical Disclosure No. 24-11857580_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857580_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,580.

Summary of the Inventive Concept

The present inventive concept relates to adapted Lactobacillus compositions for specialized vaginal health applications, providing targeted solutions for high-altitude, emergency response, extreme cold, resource-constrained, and high-humidity environments.

Background and Problem Solved

The original patent disclosed a Lactobacillus composition with antimicrobial effects on Gardnerella vaginalis and Candida albicans. However, this composition may not be suitable for specific, niche environments where vaginal infections are more prevalent or challenging to treat. The present inventive concept addresses this limitation by adapting the composition for these unique settings, ensuring effective prevention and treatment of vaginal infections in diverse operational environments.

Detailed Description of the Inventive Concept

The adapted Lactobacillus composition comprises a cell-free supernatant of Lactobacillus paracasei MG4272 strain, which is formulated to remain stable and effective in specific environments. For high-altitude environments, the composition is designed to withstand low oxygen levels. In emergency response situations, the composition is part of a kit that includes easy-to-administer formulations. For extreme cold environments, the composition is formulated to remain stable at temperatures below -20°C. In resource-constrained environments, the composition is designed for ease of administration and minimal logistical requirements. Finally, for high-humidity environments, the composition is formulated to remain stable in humid conditions. The composition's antifungal and antimicrobial activities against Gardnerella vaginalis and Candida albicans remain unaffected in these adapted formulations.

Novelty and Inventive Step

The novelty of the present inventive concept lies in the adaptation of the Lactobacillus composition for specific, niche environments, which requires a deep understanding of the interplay between the composition's stability, the environment's challenges, and the target pathogens. The inventive step involves the formulation of the composition to address these unique challenges, ensuring effective prevention and treatment of vaginal infections in diverse operational environments.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include adapting the composition for other specialized environments, such as high-radiation or high-temperature settings. Variations of the composition could also be developed for different vaginal health applications, such as prevention of sexually transmitted infections or treatment of vaginal dryness.

Potential Commercial Applications and Market

The adapted Lactobacillus composition has significant commercial potential in the feminine hygiene and healthcare industries, particularly in niche markets focused on specialized environments. The composition could be marketed as a targeted solution for women working or living in high-altitude, emergency response, extreme cold, resource-constrained, or high-humidity environments, providing a competitive advantage in these underserved markets.

Original Patent Information

Patent NumberUS 11,857,580
TitleLactobacillus having antimicrobial effect on Gardnerella vaginalis and Candida albicans
Assignee(s)Mediogen Co., Ltd.