Enhanced Iron Absorption and Gut Health System

Publication ID: 24-11857583_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Iron Absorption and Gut Health System,” Published Technical Disclosure No. 24-11857583_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857583_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,583.

Summary of the Inventive Concept

An innovative system for improving iron absorption and gut health through targeted release of Lactiplantibacillus plantarum TCI837 in the small intestine, enhancing symbiotic growth with prebiotic fibers, and utilizing iron chelates for optimal supplementation.

Background and Problem Solved

The original patent, Lactiplantibacillus plantarum TCI837, methods for using the same, and iron supplement composition having the same, has limitations in terms of iron absorption and gut health. The new inventive concept addresses these limitations by providing a more efficient and targeted approach to iron supplementation and gut microbiota enhancement.

Detailed Description of the Inventive Concept

The new inventive concept comprises a system for improving iron absorption and gut health, which includes a probiotic composition of Lactiplantibacillus plantarum TCI837 encapsulated in a pH-sensitive coating for targeted release in the small intestine. Additionally, the system involves administering a combination of the Lactiplantibacillus plantarum TCI837 with a prebiotic fiber to promote symbiotic growth. The system also utilizes an iron chelate, selected from the group consisting of ferrous sulfate, ferrous gluconate, and ferric citrate, to enhance iron absorption. Furthermore, the system can be prepared through a process involving fermenting the Lactiplantibacillus plantarum TCI837 in a medium containing an iron source, and then freeze-drying the fermented medium.

Novelty and Inventive Step

The new claims provide a novel and non-obvious approach to iron supplementation and gut health by targeting the release of Lactiplantibacillus plantarum TCI837 in the small intestine, enhancing symbiotic growth with prebiotic fibers, and utilizing iron chelates. These features distinguish the new inventive concept from the original patent and provide a significant improvement in iron absorption and gut health.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the type of prebiotic fiber used, modifying the pH-sensitive coating to optimize release in the small intestine, or utilizing different iron chelates to enhance absorption. Additionally, the system could be adapted for use in different populations, such as pediatric or geriatric populations, or for use in conjunction with other nutritional supplements.

Potential Commercial Applications and Market

The enhanced iron absorption and gut health system has significant commercial potential in the nutritional supplement industry, particularly in the areas of probiotics and iron supplementation. The system could be marketed as a premium product for individuals seeking to improve their iron levels and overall gut health, with potential applications in the food, beverage, and pharmaceutical industries.

Field of Art

Microbiology, Probiotics, and Nutritional Supplementation, with expertise in bacterial strain development, microbiome interactions, and iron absorption technologies

Person of Ordinary Skill (PHOSITA) Profile

A researcher or practitioner with advanced degree in microbiology or nutritional sciences, familiar with probiotic strain characterization, microbiological fermentation techniques, and nutritional supplement formulation strategies

Obviousness Rationale

A PHOSITA would recognize that the PTD represents predictable variations on the source patent's core technology of Lactiplantibacillus plantarum TCI837 for iron absorption. The disclosed modifications such as pH-sensitive encapsulation, prebiotic combination, and iron chelate selection represent standard optimization techniques within probiotic supplement development. These variations would be considered routine engineering adaptations that a skilled practitioner would readily conceive when seeking to improve the original iron supplementation method.

Obvious Combinations & Variations

Source Patent Element
Method of administering Lactiplantibacillus plantarum TCI837 for iron supplementation
PTD Variation
pH-sensitive encapsulation for targeted small intestine release
Obviousness Reasoning
Targeted drug/supplement delivery using pH-sensitive coatings is a known technique in pharmaceutical formulation, representing a predictable solution for improving probiotic viability and localized effectiveness
Source Patent Element
Iron supplementation using Lactiplantibacillus plantarum TCI837
PTD Variation
Combining probiotic with prebiotic fiber for symbiotic growth
Obviousness Reasoning
Symbiotic formulations combining probiotics with prebiotics are well-established in microbiological research, representing a standard approach to enhancing microbial colonization and functional effectiveness
Source Patent Element
Basic iron supplementation method
PTD Variation
Utilizing specific iron chelates like ferrous sulfate, ferrous gluconate, and ferric citrate
Obviousness Reasoning
Selection of different iron chelation forms is a known strategy for improving mineral absorption, representing a finite set of predictable chemical modifications within nutritional supplement design
Source Patent Element
Bacterial strain administration method
PTD Variation
Fermentation and freeze-drying preparation process for the probiotic supplement
Obviousness Reasoning
Fermentation and freeze-drying are standard preservation techniques in probiotic production, representing routine process optimization that would be obvious to a skilled microbiologist
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857583 and the disclosed variations, a person of ordinary skill in the art would find the claimed innovations of the published technical disclosure to represent obvious extensions of the prior art. The systematic modifications to Lactiplantibacillus plantarum TCI837 delivery, including pH-sensitive encapsulation, prebiotic combination, and iron chelate selection, constitute predictable variations that would be readily conceived by a skilled practitioner seeking to optimize iron absorption and probiotic effectiveness.

Original Patent Information

Patent NumberUS 11,857,583
TitleLactiplantibacillus plantarum TCI837, methods for using the same, and iron supplement composition having the same
Assignee(s)TCI CO., LTD.