Enhanced Iron Supplement Composition and Methods Using Lactiplantibacillus plantarum TCI837

The present inventive concept relates to novel compositions and methods for supplementing iron, promoting iron absorption, and improving gut microbiota using Lactiplantibacillus plantarum TCI837, offering enhanced efficacy and targeted delivery.

The original patent disclosed Lactiplantibacillus plantarum TCI837 as an effective means for supplementing iron and promoting iron absorption. However, it had limitations in terms of targeted delivery, gut microbiota improvement, and iron absorption enhancement. The present inventive concept addresses these limitations by introducing controlled-release capsules, prebiotics, pH-dependent coatings, and synbiotics to create a more efficient and effective iron supplement composition.

The inventive concept comprises novel compositions and methods that utilize Lactiplantibacillus plantarum TCI837 in combination with advanced delivery systems and synergistic components. Specifically, the system for supplementing iron includes a controlled-release capsule for delayed release of the bacteria in the small intestine, and an iron supplement composition. The method for promoting absorption of iron involves administering a composition comprising an effective dose of Lactiplantibacillus plantarum TCI837 and a prebiotic for enhancing the growth of the bacteria. The composition for supplementing iron features Lactiplantibacillus plantarum TCI837, an iron supplement, and a pH-dependent coating for targeted release in the small intestine. Additionally, the method for improving gut microbiota involves administering a composition comprising an effective dose of Lactiplantibacillus plantarum TCI837 and a synbiotic for promoting the growth of beneficial bacteria. A kit for supplementing iron is also provided, comprising a container holding Lactiplantibacillus plantarum TCI837, an iron supplement, and instructions for administering the composition to a subject in need thereof.

The present inventive concept offers a novel combination of Lactiplantibacillus plantarum TCI837 with advanced delivery systems and synergistic components, providing enhanced efficacy and targeted delivery. The controlled-release capsule, prebiotic, pH-dependent coating, and synbiotic components introduce a new level of sophistication in iron supplement compositions, making the inventive concept non-obvious compared to the original patent.

Alternative embodiments of the inventive concept may include different types of controlled-release capsules, prebiotics, pH-dependent coatings, and synbiotics. Variations of the composition may include additional nutrients or bioactive compounds to enhance iron absorption or gut health. The inventive concept may also be adapted for use in different forms, such as tablets, powders, or liquids, or for administration through different routes, such as intravenous or topical.

The present inventive concept has significant commercial potential in the iron supplement market, which is projected to grow due to the increasing prevalence of iron deficiency and anemia. The targeted delivery and enhanced efficacy of the inventive concept make it an attractive solution for pharmaceutical companies, nutraceutical manufacturers, and healthcare providers. The inventive concept may also find applications in the food and beverage industry, where iron-fortified products are in high demand.