Intelligent Oncolytic Virus Therapy Platform

Publication ID: 24-11857584_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Intelligent Oncolytic Virus Therapy Platform,” Published Technical Disclosure No. 24-11857584_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857584_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,584.

Summary of the Inventive Concept

A novel system integrating oncolytic viruses with AI, IoT, blockchain, and advanced biomaterials for personalized, adaptive, and secure cancer treatment.

Background and Problem Solved

The original patent disclosed an innovative method for enhancing the antitumor effect of oncolytic viruses using oxaliplatin. However, it had limitations in terms of personalized treatment, real-time monitoring, and secure data management. The new inventive concept addresses these limitations by integrating the patented method with cutting-edge technologies.

Detailed Description of the Inventive Concept

The Intelligent Oncolytic Virus Therapy Platform comprises five key components: (1) an oncolytic virus growth module integrated with an AI-powered genomics analysis platform, (2) IoT-enabled biosensors for real-time monitoring, (3) a blockchain-based decentralized data management system, (4) a composite biomaterial for targeted virus delivery, and (5) a machine learning model for predicting virus resistance. These components work together to provide personalized treatment regimens, adaptive virus strain selection, and secure data management.

Novelty and Inventive Step

The new claims introduce a synergistic combination of oncolytic viruses with AI, IoT, blockchain, and advanced biomaterials, which is not obvious from the original patent. The integration of these distinct technologies enables a novel system for personalized, adaptive, and secure cancer treatment.

Alternative Embodiments and Variations

Alternative embodiments may include using different AI algorithms, IoT sensor configurations, or blockchain protocols. Variations may involve incorporating additional technologies, such as CRISPR gene editing or nanotechnology, to further enhance the platform's capabilities.

Potential Commercial Applications and Market

The Intelligent Oncolytic Virus Therapy Platform has significant commercial potential in the cancer treatment market, with potential applications in personalized medicine, precision oncology, and digital health. The market for oncolytic virus therapy is expected to grow substantially in the coming years, driven by increasing demand for effective and targeted cancer treatments.

CPC Classifications

SectionClassGroup
A A61 A61K35/768
A A61 A61K31/282
A A61 A61K31/4745
A A61 A61K31/513
A A61 A61P35/00
C C12 C12N7/00
C C12 C12N2770/32332

Original Patent Information

Patent NumberUS 11,857,584
TitleOncolytic virus growth method and antitumor agent
Assignee(s)KABUSHIKI KAISHA YAKULT HONSHA