Synergistic Oncolytic Virus Systems for Personalized Cancer Treatment
Legal Citation
Summary of the Inventive Concept
This invention integrates oncolytic viruses with improved safety and anticancer effect with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for personalized cancer treatment.
Background and Problem Solved
The original patent disclosed an oncolytic virus with improved safety and anticancer effect. However, there was a need to further enhance the virus's efficacy and safety by leveraging advancements in AI, IoT, blockchain, and new materials. This inventive concept addresses this limitation by combining the oncolytic virus with these technologies to create a synergistic system.
Detailed Description of the Inventive Concept
The inventive concept comprises a system for personalized cancer treatment, wherein the oncolytic virus is administered in combination with a machine learning-based diagnostic tool to identify optimal treatment regimens for individual patients. Additionally, the system integrates a blockchain-based platform to securely store and share genetic information of the virus, and an IoT-enabled device for real-time monitoring of virus efficacy and toxicity in patients. Furthermore, the system utilizes AI-powered analysis to predict optimal virus variants and a nanomaterial-based delivery system to enhance tumor specificity and reduce systemic toxicity.
Novelty and Inventive Step
The new claims introduce a synergistic combination of the oncolytic virus with AI, IoT, blockchain, and new materials, which is not obvious from the original patent. The integration of these technologies enables a more effective and personalized cancer treatment approach.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT devices, or blockchain platforms. Additionally, the system could be adapted for use with other types of viruses or cancer therapies.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the cancer treatment market, particularly in the area of personalized medicine. The system's ability to provide targeted and effective treatment regimens could lead to improved patient outcomes and reduced healthcare costs.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K35/768 |
| A | A61 | A61K9/0019 |
| A | A61 | A61K31/708 |
| C | C12 | C12N15/86 |
| C | C12 | C12N2710/24111 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biotechnology and medical virology, specifically oncolytic virus engineering and personalized cancer therapeutics, requiring advanced degrees in molecular biology, virology, or biomedical engineering with expertise in genetic modification and therapeutic vector design
Person of Ordinary Skill (PHOSITA) Profile
A researcher or biotechnology professional with advanced training in viral engineering, cancer therapeutics, and computational biology, capable of integrating multiple technological platforms for therapeutic innovation
Obviousness Rationale
A PHOSITA would recognize that integrating computational technologies with oncolytic virus platforms represents a predictable extension of existing therapeutic engineering approaches. The combination of AI, IoT, and blockchain with viral vector technologies follows established patterns of technological convergence in personalized medicine. The disclosed variations represent logical combinations of known techniques to enhance diagnostic precision and treatment monitoring.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,585 |
|---|---|
| Title | Oncolytic virus improved in safety and anticancer effect |
| Assignee(s) | BIONOXX INC. |