Synergistic Oncolytic Virus Systems for Personalized Cancer Treatment

Publication ID: 24-11857585_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Oncolytic Virus Systems for Personalized Cancer Treatment,” Published Technical Disclosure No. 24-11857585_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857585_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,585.

Summary of the Inventive Concept

This invention integrates oncolytic viruses with improved safety and anticancer effect with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for personalized cancer treatment.

Background and Problem Solved

The original patent disclosed an oncolytic virus with improved safety and anticancer effect. However, there was a need to further enhance the virus's efficacy and safety by leveraging advancements in AI, IoT, blockchain, and new materials. This inventive concept addresses this limitation by combining the oncolytic virus with these technologies to create a synergistic system.

Detailed Description of the Inventive Concept

The inventive concept comprises a system for personalized cancer treatment, wherein the oncolytic virus is administered in combination with a machine learning-based diagnostic tool to identify optimal treatment regimens for individual patients. Additionally, the system integrates a blockchain-based platform to securely store and share genetic information of the virus, and an IoT-enabled device for real-time monitoring of virus efficacy and toxicity in patients. Furthermore, the system utilizes AI-powered analysis to predict optimal virus variants and a nanomaterial-based delivery system to enhance tumor specificity and reduce systemic toxicity.

Novelty and Inventive Step

The new claims introduce a synergistic combination of the oncolytic virus with AI, IoT, blockchain, and new materials, which is not obvious from the original patent. The integration of these technologies enables a more effective and personalized cancer treatment approach.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT devices, or blockchain platforms. Additionally, the system could be adapted for use with other types of viruses or cancer therapies.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the cancer treatment market, particularly in the area of personalized medicine. The system's ability to provide targeted and effective treatment regimens could lead to improved patient outcomes and reduced healthcare costs.

CPC Classifications

SectionClassGroup
A A61 A61K35/768
A A61 A61K9/0019
A A61 A61K31/708
C C12 C12N15/86
C C12 C12N2710/24111

Original Patent Information

Patent NumberUS 11,857,585
TitleOncolytic virus improved in safety and anticancer effect
Assignee(s)BIONOXX INC.