Enhanced Pharmaceutical Composition for Gynecological Diseases

Publication ID: 24-11857586_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Pharmaceutical Composition for Gynecological Diseases,” Published Technical Disclosure No. 24-11857586_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857586_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,586.

Summary of the Inventive Concept

An improved pharmaceutical composition for preventing or treating gynecological diseases, featuring Sarcodon aspratus extracts as active ingredients, with enhanced efficacy, reduced side effects, and personalized treatment options.

Background and Problem Solved

The original patent, relating to a pharmaceutical composition for preventing or treating gynecological diseases, has limitations in terms of efficacy, side effects, and individualized treatment. The present inventive concept addresses these limitations by introducing novel formulations, delivery methods, and diagnostic tools, thereby providing a more effective and safer treatment option.

Detailed Description of the Inventive Concept

The inventive concept comprises a pharmaceutical composition containing Sarcodon aspratus extracts as active ingredients, with various enhancements. Firstly, the composition can be formulated to provide a sustained release of the extracts over a prolonged period, reducing side effects and improving efficacy. Secondly, the composition can be administered in a transdermal patch form, providing a localized and controlled release of the extracts. Additionally, the composition can include a bioavailability enhancer, increasing the absorption of the extracts into the bloodstream. Furthermore, the inventive concept includes a diagnostic tool for identifying subjects likely to benefit from the composition, based on genetic markers associated with gynecological diseases. Lastly, the composition can be personalized to an individual's genetic profile and medical history, optimizing efficacy and minimizing side effects.

Novelty and Inventive Step

The inventive concept's novelty lies in the combination of Sarcodon aspratus extracts with novel formulations, delivery methods, and diagnostic tools, which are not obvious from the original patent. The sustained release formulation, transdermal patch administration, bioavailability enhancer, diagnostic tool, and personalized treatment options all contribute to the inventive step, providing a significant improvement over the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include different formulations, such as nanoparticles or liposomes, to enhance bioavailability. Additionally, the diagnostic tool could be based on other biomarkers, such as hormone levels or gene expression profiles. Furthermore, the personalized treatment options could be expanded to include other factors, such as lifestyle or environmental factors.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical industry, particularly in the area of women's health. The improved efficacy and safety profile of the composition, combined with the personalized treatment options, make it an attractive solution for patients and healthcare providers. The market potential is substantial, with a growing demand for effective and targeted treatments for gynecological diseases.

CPC Classifications

SectionClassGroup
A A61 A61K36/07
A A61 A61K9/0056
A A61 A61P15/08
A A61 A61K2236/333

Field of Art

Pharmaceutical compositions for gynecological treatments, specifically focusing on herbal extracts, drug delivery systems, and personalized medicine approaches in women's health

Person of Ordinary Skill (PHOSITA) Profile

A pharmaceutical scientist or biotechnologist with expertise in herbal medicine, drug formulation, targeted drug delivery, and personalized medical interventions, holding an advanced degree with 3-5 years of research experience in women's health pharmaceuticals

Obviousness Rationale

A skilled practitioner would recognize that the source patent's fundamental composition of Sarcodon aspratus extracts provides a clear technological foundation for incremental improvements in delivery, bioavailability, and personalization. The PTD's variations represent predictable engineering solutions that would be apparent to one skilled in pharmaceutical development, leveraging known techniques in sustained release, transdermal delivery, and diagnostic-guided treatment strategies.

Obvious Combinations & Variations

Source Patent Element
Pharmaceutical composition containing Sarcodon aspratus extracts for gynecological disease treatment
PTD Variation
Sustained release formulation of the extracts to reduce side effects and improve efficacy
Obviousness Reasoning
Sustained release drug delivery is a well-established pharmaceutical technique, and a PHOSITA would recognize this as a predictable optimization of the original composition's therapeutic approach
Source Patent Element
Method of administering herbal extract composition
PTD Variation
Transdermal patch delivery method for localized and controlled extract release
Obviousness Reasoning
Transdermal drug delivery is a known alternative administration technique, particularly for hormonal and localized treatments, representing a routine design choice for a skilled practitioner
Source Patent Element
Pharmaceutical composition for gynecological disease treatment
PTD Variation
Addition of bioavailability enhancers to improve extract absorption
Obviousness Reasoning
Enhancing drug absorption through excipients and delivery mechanisms is a standard pharmaceutical engineering approach, representing an obvious optimization to improve therapeutic effectiveness
Source Patent Element
Method of treating gynecological diseases
PTD Variation
Genetic marker-based diagnostic tool for personalized treatment selection
Obviousness Reasoning
Personalized medicine and diagnostic-guided treatment are emerging standard practices, and a PHOSITA would find the integration of genetic screening with herbal extract treatment a predictable technological progression
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed in the Published Technical Disclosure render obvious any patent claims covering incremental improvements to the pharmaceutical composition of US Patent 11857586, as the claimed variations represent predictable engineering solutions within the ordinary skill of a person trained in pharmaceutical development and personalized medicine approaches.

Original Patent Information

Patent NumberUS 11,857,586
TitlePharmaceutical composition for preventing or treating gynecological diseases containing Sarcodon aspratus extracts as active ingredient