Enhanced Bioactive Extract Composition with Synergistic Immune-Boosting and Anti-Inflammatory Effects

Publication ID: 24-11857587_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Bioactive Extract Composition with Synergistic Immune-Boosting and Anti-Inflammatory Effects,” Published Technical Disclosure No. 24-11857587_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857587_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,587.

Summary of the Inventive Concept

An improved bioactive extract composition with enhanced immune-boosting and anti-inflammatory properties, achieved through strategic combinations of fungal extract components, natural antioxidants, probiotic microorganisms, and fruit extracts.

Background and Problem Solved

The original patent disclosed a composition including fungal extract components from medicinal fungal species, but it had limitations in terms of bioavailability and synergistic effects. The new inventive concept addresses these limitations by introducing natural antioxidants, probiotic microorganisms, and fruit extracts to create a more potent and effective bioactive extract composition.

Detailed Description of the Inventive Concept

The new inventive concept involves combining fungal extract components from medicinal fungal species with natural antioxidants, such as vitamin C, vitamin E, and beta-carotene, to provide a synergistic immune-boosting effect. Additionally, the composition can be fermented with probiotic microorganisms to increase the bioavailability of the fungal extract components. The composition can also be mixed with fruit extracts, such as Kakadu plum, Acai berry, and Goji berry, to enhance its nutritional value. Furthermore, the system for producing the bioactive extract composition can be optimized with a temperature control system to promote the growth of the medicinal fungal species.

Novelty and Inventive Step

The new claims introduce novel combinations of fungal extract components, natural antioxidants, probiotic microorganisms, and fruit extracts, which provide a synergistic immune-boosting and anti-inflammatory effect. The inventive step lies in the strategic selection and combination of these components to achieve a more potent and effective bioactive extract composition.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different medicinal fungal species, varying the concentrations of the fungal extract components, or incorporating additional natural antioxidants or anti-inflammatory compounds. Variations could also involve using different fermentation methods or optimizing the system for producing the bioactive extract composition.

Potential Commercial Applications and Market

The enhanced bioactive extract composition has potential commercial applications in the pharmaceutical, nutraceutical, and cosmetic industries, particularly in the development of immune-boosting and anti-inflammatory products. The target market includes consumers seeking natural and effective health supplements, as well as companies developing products for immune system support and overall wellness.

CPC Classifications

SectionClassGroup
A A61 A61K36/074
A A61 A61K36/185
A A61 A61K2236/333

Field of Art

Biotechnology and pharmaceutical compositions, specifically focused on medicinal fungal extracts with immune-boosting and therapeutic properties, requiring expertise in microbiology, extraction techniques, and natural product formulation

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degree in biotechnology or pharmaceutical sciences, experienced in fungal cultivation, extraction methodologies, and natural product composition design, familiar with medicinal mushroom research and nutraceutical development

Obviousness Rationale

A person skilled in the art would recognize that enhancing the source patent's bioactive fungal extract through strategic combinations of antioxidants, probiotics, and fruit extracts represents a predictable variation within established nutraceutical development practices. The proposed modifications leverage known synergistic techniques for improving bioavailability and therapeutic potential of fungal extracts. These extensions demonstrate standard incremental innovation typical in natural product formulation research.

Obvious Combinations & Variations

Source Patent Element
Fungal extract components from medicinal fungal species grown on grains
PTD Variation
Adding natural antioxidants like vitamin C, vitamin E, and beta-carotene to enhance immune-boosting properties
Obviousness Reasoning
Known technique of supplementing botanical extracts with complementary antioxidants to improve therapeutic efficacy, representing a predictable optimization within nutritional science
Source Patent Element
Extraction method involving ethanol concentration between 10-60%
PTD Variation
Incorporating probiotic fermentation to increase bioavailability of fungal extract components
Obviousness Reasoning
Established biotechnological approach of using microbial fermentation to enhance extract potency and absorption, representing a standard method of extract modification
Source Patent Element
Composition with potential antiviral and immune-boosting activities
PTD Variation
Adding fruit extracts like Kakadu plum, Acai berry, and Goji berry to enhance nutritional profile
Obviousness Reasoning
Routine practice of combining multiple natural ingredients to create synergistic nutritional compositions, demonstrating predictable design choice in nutraceutical development
Source Patent Element
Fungal species cultivation method
PTD Variation
Implementing temperature control system to optimize fungal species growth
Obviousness Reasoning
Standard engineering approach of process optimization, representing a predictable technical improvement in biological cultivation techniques
Source Patent Element
Immune-boosting composition
PTD Variation
Incorporating anti-inflammatory compounds like curcumin, gingerol, and capsaicin
Obviousness Reasoning
Well-known strategy of combining complementary natural compounds to enhance therapeutic potential, reflecting standard practice in botanical medicine research
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857587, a person having ordinary skill in the art would find the variations disclosed in this publication to represent obvious extensions of the prior art, rendering potential patent claims covering similar compositions obvious and unpatentable under 35 U.S.C. ยง 103, as the proposed modifications constitute predictable variations within established nutraceutical development methodologies.

Original Patent Information

Patent NumberUS 11,857,587
TitleBioactive extract