Enhanced Water-Soluble Cannabinoid and/or Terpene Extracts with Improved Bioavailability and Adjustable Bulk Density
Legal Citation
Summary of the Inventive Concept
The present inventive concept relates to a system, method, and composition for preparing and manufacturing water-soluble, powdered cannabinoid and/or terpene extracts with enhanced bioavailability and adjustable bulk density, overcoming the limitations of existing extraction methods.
Background and Problem Solved
The original patent disclosed a water-soluble, powdered cannabinoid and/or terpene extract, but it had limitations in terms of bioavailability and bulk density adjustability. The present inventive concept addresses these limitations by introducing a combination of emulsifiers to enhance bioavailability and a novel manufacturing process to achieve adjustable bulk density.
Detailed Description of the Inventive Concept
The inventive concept comprises a system for preparing a water-soluble, powdered cannabinoid and/or terpene extract, involving a solvent and a combination of emulsifiers selected to enhance bioavailability. The method involves mixing the extract with the solvent and emulsifiers, followed by spray-drying to form a powder. The resulting powder has an adjustable bulk density based on the final dosage form desired. The composition further comprises a pH-dependent release agent and is loaded onto a mesoporous silica.
Novelty and Inventive Step
The new claims introduce a novel combination of emulsifiers to enhance bioavailability, a manufacturing process that achieves adjustable bulk density, and a pH-dependent release agent, which are not present in the original patent. These features provide a non-obvious improvement over the existing extraction methods.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include using different types of emulsifiers, solvents, or release agents. Variations may also include different manufacturing processes, such as freeze-drying or granulation, to achieve the desired bulk density and bioavailability.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential in the pharmaceutical and nutraceutical industries, particularly in the development of cannabis-based products with improved bioavailability and adjustable dosage forms. The target market includes manufacturers of cannabis-based products, pharmaceutical companies, and research institutions.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K36/185 |
| A | A61 | A61K9/107 |
| A | A61 | A61K47/02 |
| A | A61 | A61K47/36 |
| A | A61 | A61K47/40 |
| A | A61 | A61K47/44 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical cannabinoid extraction and formulation technologies, with expertise in solvent extraction, emulsification, powder processing, and drug delivery systems for botanical compounds
Person of Ordinary Skill (PHOSITA) Profile
A professional with advanced degrees in pharmaceutical sciences, chemical engineering, or related fields, possessing knowledge of extraction techniques, emulsification processes, and drug formulation strategies for botanical compounds
Obviousness Rationale
A PHOSITA would recognize that the PTD represents predictable variations on the source patent's core cannabinoid extraction methodology, utilizing standard pharmaceutical engineering techniques to incrementally improve extract solubility, bioavailability, and processing flexibility. The disclosed modifications represent routine optimization of known extraction and formulation strategies within the cannabinoid pharmaceutical domain. The technical variations demonstrate expected engineering adaptations that would be apparent to a skilled practitioner seeking to enhance cannabinoid extract performance.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,589 |
|---|---|
| Title | Water-soluble, powdered cannabinoid and/or terpene extract |
| Assignee(s) | MEDPHARM HOLDINGS, LLC |