Enhanced Water-Soluble Cannabinoid and/or Terpene Extracts with Improved Bioavailability and Adjustable Bulk Density

Publication ID: 24-11857589_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Water-Soluble Cannabinoid and/or Terpene Extracts with Improved Bioavailability and Adjustable Bulk Density,” Published Technical Disclosure No. 24-11857589_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857589_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,589.

Summary of the Inventive Concept

The present inventive concept relates to a system, method, and composition for preparing and manufacturing water-soluble, powdered cannabinoid and/or terpene extracts with enhanced bioavailability and adjustable bulk density, overcoming the limitations of existing extraction methods.

Background and Problem Solved

The original patent disclosed a water-soluble, powdered cannabinoid and/or terpene extract, but it had limitations in terms of bioavailability and bulk density adjustability. The present inventive concept addresses these limitations by introducing a combination of emulsifiers to enhance bioavailability and a novel manufacturing process to achieve adjustable bulk density.

Detailed Description of the Inventive Concept

The inventive concept comprises a system for preparing a water-soluble, powdered cannabinoid and/or terpene extract, involving a solvent and a combination of emulsifiers selected to enhance bioavailability. The method involves mixing the extract with the solvent and emulsifiers, followed by spray-drying to form a powder. The resulting powder has an adjustable bulk density based on the final dosage form desired. The composition further comprises a pH-dependent release agent and is loaded onto a mesoporous silica.

Novelty and Inventive Step

The new claims introduce a novel combination of emulsifiers to enhance bioavailability, a manufacturing process that achieves adjustable bulk density, and a pH-dependent release agent, which are not present in the original patent. These features provide a non-obvious improvement over the existing extraction methods.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include using different types of emulsifiers, solvents, or release agents. Variations may also include different manufacturing processes, such as freeze-drying or granulation, to achieve the desired bulk density and bioavailability.

Potential Commercial Applications and Market

The present inventive concept has significant commercial potential in the pharmaceutical and nutraceutical industries, particularly in the development of cannabis-based products with improved bioavailability and adjustable dosage forms. The target market includes manufacturers of cannabis-based products, pharmaceutical companies, and research institutions.

CPC Classifications

SectionClassGroup
A A61 A61K36/185
A A61 A61K9/107
A A61 A61K47/02
A A61 A61K47/36
A A61 A61K47/40
A A61 A61K47/44

Original Patent Information

Patent NumberUS 11,857,589
TitleWater-soluble, powdered cannabinoid and/or terpene extract
Assignee(s)MEDPHARM HOLDINGS, LLC