Personalized Cannabinoid and/or Terpene Extract Compositions with Enhanced Bioavailability

Publication ID: 24-11857589_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Cannabinoid and/or Terpene Extract Compositions with Enhanced Bioavailability,” Published Technical Disclosure No. 24-11857589_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857589_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,589.

Summary of the Inventive Concept

This inventive concept envisions a next-generation system for generating personalized cannabinoid and/or terpene extract compositions with tunable bioavailability, leveraging advanced data processing, solvent selection, emulsifier optimization, and nanoparticle carrier systems to revolutionize the field of cannabinoid-based therapies.

Background and Problem Solved

The original patent disclosed a water-soluble, powdered cannabinoid and/or terpene extract, but it had limitations in terms of bioavailability and personalized dosing. The new inventive concept addresses these limitations by introducing a modular, automated system capable of producing a range of extract compositions with varying bioavailability profiles, tailored to individual biometric data.

Detailed Description of the Inventive Concept

The inventive concept comprises a data processing unit that analyzes individual biometric data to determine the optimal cannabinoid and/or terpene extract composition. A solvent selection module and an emulsifier optimization module work in tandem to solubilize and emulsify the extract, respectively. The resulting emulsified extract is then lyophilized to form a powder with adjustable particle size and surface area, allowing for tunable bioavailability. A nanoparticle carrier system can be integrated to enable targeted delivery of the extract to specific tissues or organs. The system can be monitored and optimized in real-time using spectroscopic techniques and a database of known bioavailability profiles.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the field of cannabinoid-based therapies by enabling personalized, data-driven extract compositions with enhanced bioavailability. The inventive concept's novelty lies in the integration of advanced data processing, solvent selection, emulsifier optimization, and nanoparticle carrier systems to create a modular, automated system capable of producing a range of extract compositions with varying bioavailability profiles.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of machine learning algorithms to predict optimal extract compositions based on individual biometric data, or the integration of additional modules for real-time monitoring of extract composition bioavailability. Variations of the inventive concept could also include the use of different solvent selection modules or emulsifier optimization modules to accommodate various extract compositions and bioavailability profiles.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical, nutraceutical, and wellness industries, where personalized cannabinoid-based therapies are increasingly in demand. The system's ability to produce a range of extract compositions with varying bioavailability profiles could revolutionize the treatment of various diseases and disorders, including chronic pain, inflammation, and anxiety disorders.

CPC Classifications

SectionClassGroup
A A61 A61K36/185
A A61 A61K9/107
A A61 A61K47/02
A A61 A61K47/36
A A61 A61K47/40
A A61 A61K47/44

Field of Art

Pharmaceutical and chemical engineering, specifically cannabinoid extract processing and formulation technologies, with expertise in solubilization, emulsification, and powder preparation techniques for bioactive compounds

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in chemical engineering, pharmaceutical sciences, or related fields, possessing knowledge of solvent extraction, emulsification techniques, powder processing, and drug delivery systems, with experience in cannabinoid and terpene extract formulations

Obviousness Rationale

A person of ordinary skill would recognize that the PTD represents a predictable extension of the source patent's cannabinoid extract processing techniques, applying known pharmaceutical engineering principles to enhance extract bioavailability through data-driven personalization and advanced processing methods. The disclosed variations represent logical combinations of existing techniques in extract preparation, solubilization, and delivery systems. The technical modifications would be considered routine optimization within the field of cannabinoid extract formulation.

Obvious Combinations & Variations

Source Patent Element
Water-soluble, micronized, emulsified powdered cannabis extract complexed with cyclodextrin
PTD Variation
Personalized extract composition with data-driven solvent and emulsifier selection for tunable bioavailability
Obviousness Reasoning
Predictable application of known pharmaceutical engineering techniques to extend extract processing capabilities, representing a design choice for improving extract performance
Source Patent Element
Powdered extract loaded onto mesoporous silica
PTD Variation
Nanoparticle carrier system for targeted delivery of extract to specific tissues or organs
Obviousness Reasoning
Known technique of using carrier systems to enhance drug delivery, representing a standard approach in pharmaceutical formulation for improving compound bioavailability
Source Patent Element
Cannabis extract complexed with maltodextrin and acacia
PTD Variation
Advanced emulsifier optimization module for creating customized extract compositions
Obviousness Reasoning
Routine optimization of emulsification techniques, applying known principles of pharmaceutical formulation to create more sophisticated extract processing methods
Source Patent Element
Water-soluble powdered cannabinoid extract with adjustable bulk density
PTD Variation
Lyophilization process creating powder with adjustable particle size and surface area for enhanced bioavailability
Obviousness Reasoning
Predictable extension of existing powder processing techniques, representing a standard approach to modifying extract characteristics for improved performance
Source Patent Element
Cannabinoid extract processing method
PTD Variation
Integration of machine learning and spectroscopic techniques for real-time composition monitoring and optimization
Obviousness Reasoning
Application of known data processing and analytical techniques to pharmaceutical formulation, representing a logical technological progression in extract development
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857589 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed cannabinoid extract processing techniques obvious and anticipated, as the PTD demonstrates that the claimed innovations represent predictable combinations of known pharmaceutical engineering methods for extract preparation, solubilization, and delivery optimization.

Original Patent Information

Patent NumberUS 11,857,589
TitleWater-soluble, powdered cannabinoid and/or terpene extract
Assignee(s)MEDPHARM HOLDINGS, LLC