Curcumin Compositions for Specialized Applications

Publication ID: 24-11857594_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Curcumin Compositions for Specialized Applications,” Published Technical Disclosure No. 24-11857594_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857594_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,594.

Summary of the Inventive Concept

Adaptations of curcumin compositions for specific, narrow markets or unique operational environments, such as disaster relief, high-security needs, and extreme weather conditions.

Background and Problem Solved

The original patent disclosed curcumin compositions as NK3 antagonists, but the inventors recognized the need for specialized variations to address unique challenges in various environments. The new inventive concept addresses these limitations by providing tailored formulations and delivery systems for high-stress, resource-constrained, or extreme weather situations.

Detailed Description of the Inventive Concept

The new claims introduce curcumin compositions formulated for rapid deployment in extreme weather conditions, covert administration in high-security zones, and emergency response situations. These compositions feature optimized ratios of diferuloylmethane to DMC, tetrahydrocurcumin to dihydrocurcumin, hexahydrocurcumin to octahydrocurcumin, and other curcuminoids. The inventive concept also encompasses novel packaging and delivery systems, such as portable, waterproof containers and water purification systems, to ensure the compositions remain effective in challenging environments.

Novelty and Inventive Step

The new claims introduce a novel combination of curcuminoids and formulations tailored to specific, high-stress environments, which is not anticipated by the original patent. The inventive concept's focus on specialized applications and unique operational environments constitutes a non-obvious advancement over the prior art.

Alternative Embodiments and Variations

Other embodiments of the inventive concept could include curcumin compositions for use in space exploration, search and rescue operations, or remote medical treatment in areas with limited access to medical resources. Variations may also include different ratios of curcuminoids, alternative delivery systems, or additional components to enhance the compositions' efficacy and stability.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including disaster relief, emergency response, and high-security medical services. The target market includes government agencies, non-governmental organizations, and private companies operating in high-stress environments.

CPC Classifications

SectionClassGroup
A A61 A61K36/9066
A A61 A61K31/26
A A61 A61K36/82
A A61 A61P15/12

Field of Art

Pharmaceutical compositions, specifically natural product-based therapeutic formulations with a focus on curcuminoid compounds and their medical applications, requiring advanced knowledge of organic chemistry, pharmacology, and natural product extraction techniques

Person of Ordinary Skill (PHOSITA) Profile

A researcher or pharmaceutical formulation specialist with advanced degrees in chemistry or pharmacology, experienced in natural product extraction, compound modification, and therapeutic composition design, familiar with curcuminoid structural variations and medical applications

Obviousness Rationale

A PHOSITA would recognize that the source patent's foundational work on curcumin compositions provides a clear framework for exploring derivative formulations targeting specialized environments. The PTD's variations represent predictable extensions of known curcuminoid modification techniques, utilizing standard pharmaceutical engineering approaches to adapt the base composition for specific operational contexts. The disclosed ratios and formulation strategies demonstrate incremental modifications that would be readily conceived by a skilled practitioner familiar with natural product composition design.

Obvious Combinations & Variations

Source Patent Element
Curcumin composition with specific synergistic ratios of curcumin, green tea extract, and phycocyanin
PTD Variation
Curcumin compositions with modified curcuminoid ratios targeting specific environmental conditions
Obviousness Reasoning
Predictable variation using known compound modification techniques, representing a design choice within standard pharmaceutical formulation practices
Source Patent Element
Compositional ratios between 4.5:4.5:1 and 7.2:1.8:1 of different compounds
PTD Variation
Introducing new ratios of diferuloylmethane to DMC and other curcuminoid derivatives
Obviousness Reasoning
Routine optimization of compositional ratios using known structural modification techniques, representing a finite set of predictable variations
Source Patent Element
Therapeutic composition with multiple natural product components
PTD Variation
Specialized delivery systems including portable containers and water purification integration
Obviousness Reasoning
Obvious application of standard pharmaceutical engineering principles to extend composition utility in challenging environments
Source Patent Element
Curcumin composition with multiple active compounds
PTD Variation
Formulations for specific operational contexts like disaster relief and high-security zones
Obviousness Reasoning
Predictable adaptation of known therapeutic compositions to address specific medical and operational requirements
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857594, a person of ordinary skill in the art would find the variations disclosed in the Published Technical Disclosure to represent obvious extensions of the prior art, utilizing standard pharmaceutical formulation techniques to adapt curcuminoid compositions for specialized environments. The incremental modifications demonstrate no inventive step beyond the routine skill of practitioners in natural product composition design, thereby rendering potential derivative claims obvious and unpatentable.

Original Patent Information

Patent NumberUS 11,857,594
TitleCurcumin compositions and methods of use as an NK3 antagonist
Assignee(s)JDS Therapeutics, LLC