Curcumin-based Synergistic Systems for Neurokinin-3 Receptor Modulation

Publication ID: 24-11857594_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Curcumin-based Synergistic Systems for Neurokinin-3 Receptor Modulation,” Published Technical Disclosure No. 24-11857594_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857594_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,594.

Summary of the Inventive Concept

A comprehensive system integrating curcumin compositions with distinct technologies to create a powerful platform for treating neurokinin-3 receptor-related disorders and optimizing curcumin composition efficacy.

Background and Problem Solved

The original patent identified curcumin as a potent NK3 antagonist, but its limitations included the lack of a comprehensive system for treating NK3-related disorders. The new inventive concept addresses this limitation by integrating curcumin compositions with AI, IoT, blockchain, and new materials to create a synergistic system.

Detailed Description of the Inventive Concept

The inventive concept comprises four distinct systems: a wearable device with an AI-powered analytics module for tracking neurological activity and identifying personalized treatment regimens; an IoT-enabled sensor system for monitoring physiological responses and adjusting curcumin composition formulations; a blockchain-based platform for tracking and verifying curcumin composition authenticity; and a composite material integrating curcumin with biocompatible polymers for biomedical applications. These systems work in tandem to provide a comprehensive platform for treating NK3-related disorders.

Novelty and Inventive Step

The new claims introduce novel combinations of curcumin compositions with distinct technologies, providing a synergistic system that is not obvious from the original patent. The integration of AI, IoT, blockchain, and new materials with curcumin compositions creates a new, more powerful system for treating NK3-related disorders.

Alternative Embodiments and Variations

Alternative embodiments could include integrating curcumin compositions with other distinct technologies, such as virtual reality or nanotechnology. Variations could include using different ratios of curcumin to other components or incorporating additional ingredients to enhance the system's efficacy.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and biomedical industries, particularly in the areas of neurological disorders and personalized medicine. The system's ability to provide comprehensive treatment and monitoring options could lead to improved patient outcomes and increased market share.

CPC Classifications

SectionClassGroup
A A61 A61K36/9066
A A61 A61K31/26
A A61 A61K36/82
A A61 A61P15/12

Original Patent Information

Patent NumberUS 11,857,594
TitleCurcumin compositions and methods of use as an NK3 antagonist
Assignee(s)JDS Therapeutics, LLC