Enhanced Feed Additive Compositions for Improved Livestock Performance

Publication ID: 24-11857596_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Feed Additive Compositions for Improved Livestock Performance,” Published Technical Disclosure No. 24-11857596_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857596_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,596.

Summary of the Inventive Concept

This inventive concept discloses novel methods and compositions for improving the effectiveness of coated-type feed additives for livestock, enhancing their body weight gain and feed conversion ratio.

Background and Problem Solved

The original patent addresses the growing demand for meat production, but its limitations include the potential degradation of the physiologically active substance during manufacturing and storage, as well as variable bioavailability. This inventive concept solves these problems by introducing heat shock protein inducers, optimized coating agents, and synergistic combinations of bacteriocins and antioxidants to enhance the membrane-strengthening ability and bioavailability of the active substances.

Detailed Description of the Inventive Concept

The inventive concept comprises four main aspects. Firstly, a method for enhancing the membrane-strengthening ability of a physiologically active substance by treating it with a heat shock protein inducer. Secondly, a system for optimizing the composition of a coated-type feed additive by selecting bacteriocins based on their membrane-strengthening ability and core coating agents based on their ability to enhance bioavailability. Thirdly, a coated-type feed additive composition comprising a combination of a bacteriocin and an antioxidant, where the antioxidant enhances the membrane-strengthening ability of the bacteriocin. Lastly, a method for improving the feed conversion ratio of livestock by administering a coated-type feed additive composition comprising a bacteriocin and a polysaccharide, where the polysaccharide enhances the bioavailability of the bacteriocin.

Novelty and Inventive Step

The novelty of this inventive concept lies in the introduction of heat shock protein inducers, optimized coating agents, and synergistic combinations of bacteriocins and antioxidants to enhance the membrane-strengthening ability and bioavailability of the active substances. The inventive step is the recognition of the importance of bioavailability and membrane-strengthening ability in coated-type feed additives and the development of novel methods and compositions to address these limitations.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept include the use of different heat shock protein inducers, coating agents, bacteriocins, and antioxidants. Additionally, the inventive concept could be adapted for use in different types of livestock or in combination with other feed additives.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the animal feed industry, particularly in the production of meat for human consumption. The target market includes livestock farmers, feed manufacturers, and animal health companies.

CPC Classifications

SectionClassGroup
A A61 A61K38/12
A A23 A23K10/16
A A23 A23K20/111
A A23 A23K20/142
A A23 A23K20/195
A A23 A23K20/26
A A23 A23K40/30
A A23 A23K50/75
A A61 A61K31/198
A A61 A61K31/405
A A61 A61K31/683
A A61 A61K35/747
A A61 A61K47/22
A A61 A61K47/44
A A23 A23V2400/157
A A23 A23V2400/169

Field of Art

Animal nutrition and feed technology, specifically focused on livestock feed additives with an emphasis on microbiological and physiological enhancement techniques. Requires expertise in microbiology, animal nutrition, and pharmaceutical formulation with typical educational background of PhD or Masters in animal science, microbiology, or related agricultural biotechnology disciplines

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with comprehensive understanding of livestock nutrition, bacteriocin mechanisms, feed additive formulation techniques, and knowledge of microbial interactions in animal digestive systems. Capable of systematic experimentation and incremental technological improvements

Obviousness Rationale

A person skilled in the art would recognize that the published technical disclosure represents predictable variations on the source patent's core teachings about bacteriocin-based feed additives. The PTD's proposed modifications - such as adding heat shock protein inducers, antioxidants, and polysaccharides - represent standard optimization strategies well within the knowledge of those practicing in livestock nutritional science. These variations demonstrate routine engineering approaches to enhancing the fundamental bacteriocin delivery mechanism disclosed in the original patent.

Obvious Combinations & Variations

Source Patent Element
Coated-type feed additive with bacteriocin core containing membrane-strengthening physiologically active substances
PTD Variation
Adding heat shock protein inducer to enhance membrane-strengthening capabilities
Obviousness Reasoning
Known technique of using protein stress response mechanisms to improve cellular membrane integrity, representing a predictable enhancement to existing formulation approach
Source Patent Element
Bacteriocin-based feed additive for improving livestock performance
PTD Variation
Incorporating antioxidants to enhance bacteriocin membrane-strengthening properties
Obviousness Reasoning
Routine combination of known functional ingredients to improve biological activity, demonstrating standard pharmaceutical formulation strategy
Source Patent Element
Core coating agent for controlling bacteriocin delivery in livestock feed
PTD Variation
Selecting coating agents specifically to enhance bacteriocin bioavailability
Obviousness Reasoning
Represents standard pharmaceutical engineering approach of optimizing delivery mechanisms through systematic screening and selection of excipients
Source Patent Element
Feed additive composition using microorganisms like Bacillus subtilis
PTD Variation
Adding polysaccharides to improve bacteriocin bioavailability
Obviousness Reasoning
Predictable application of known carbohydrate-based absorption enhancement techniques commonly used in nutritional and pharmaceutical formulations
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857596 and the published technical disclosure, a person having ordinary skill in the art would find the claimed variations obvious and lacking inventive step. The proposed modifications represent routine optimization strategies within the established technological framework of bacteriocin-based livestock feed additives, thereby rendering subsequent claims obvious under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,596
TitleAnimal feed additive and animal feed
Assignee(s)AJINOMOTO CO., INC.