GPCR Heteromer-based Solutions for Diverse Industries

Publication ID: 24-11857600_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “GPCR Heteromer-based Solutions for Diverse Industries,” Published Technical Disclosure No. 24-11857600_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857600_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,600.

Summary of the Inventive Concept

The inventive concept leverages the core technology of GPCR heteromer inhibitors to develop innovative solutions for various industries, including agriculture, industrial fermentation, water quality monitoring, environmental pollution mitigation, and animal health.

Background and Problem Solved

The original patent disclosed inhibitors of novel, functional GPCR heteromers, particularly CXCR4-HRH1 heteromers, for cancer treatment. However, the potential applications of GPCR heteromers extend beyond oncology. The inventive concept addresses the limitation of the original patent by exploring new use cases that capitalize on the versatility of GPCR heteromers.

Detailed Description of the Inventive Concept

The inventive concept encompasses a range of systems, methods, and devices that utilize GPCR heteromers to tackle distinct challenges in various industries. For instance, in agriculture, GPCR heteromer-based sensors can monitor and predict crop yields by detecting and quantifying GPCR heteromers in plant cells. In industrial fermentation, identifying and inhibiting specific GPCR heteromers can optimize fermentation efficiency. Similarly, GPCR heteromer-based biosensors can detect and diagnose waterborne pathogens, while a network of GPCR heteromer-based sensors can predict and mitigate environmental pollution. In animal health, GPCR heteromer inhibitors can improve growth and development in livestock.

Novelty and Inventive Step

The new claims introduce novel applications and use cases for GPCR heteromers, which are not obvious from the original patent. The inventive step lies in recognizing the potential of GPCR heteromers to solve diverse industry-specific problems and developing innovative solutions that capitalize on this potential.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include the use of different GPCR heteromers, varying sensor configurations, or alternative data analysis approaches. Additionally, the inventive concept could be adapted for use in other industries, such as biomedical diagnostics or pharmaceutical development.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential across multiple industries, including agriculture, industrial fermentation, water quality monitoring, environmental pollution mitigation, and animal health. The target market includes companies, research institutions, and government agencies operating in these industries, as well as potential partnerships with biotechnology and pharmaceutical companies.

CPC Classifications

SectionClassGroup
A A61 A61K38/195
A A61 A61K31/138
A A61 A61K31/395
A A61 A61K31/403
A A61 A61K31/451
A A61 A61K31/4545
A A61 A61K31/47
A A61 A61K31/495
A A61 A61K31/5415
A A61 A61K38/12
A A61 A61K39/3955
A A61 A61P35/00
C C07 C07K16/286
C C07 C07K16/2866
A A61 A61K2039/505
A A61 A61K2039/507
C C07 C07K2317/21
C C07 C07K2317/76

Original Patent Information

Patent NumberUS 11,857,600
TitleGPCR heteromer inhibitors and uses thereof
Assignee(s)GPCR THERAPEUTICS, INC.